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852008 Fmoc-Cys(Trt)-OH

Fmoc-Cys(Trt)-OH Novabiochem®. CAS 103213-32-7, molar mass 585.72 g/mol.

Fmoc-Cys(Trt)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 103213-32-7 Molar Mass: 585.73 g/mol Hill Formula: C₇H₃₁NO₄S
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852008
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
103213-32-7C₇H₃₁NO₄S585.73 g/mol

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      8520080100
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              8520081000
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                  Description
                  Catalogue Number852008
                  Replaces04-12-1018
                  Brand Family Novabiochem®
                  Alternate Names
                  • N-α-Fmoc-S-trityl-L-cysteine
                  Background InformationThe standard derivative for Fmoc SPPS of peptides containing Cys [1]. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation [2,3] to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP®, is to be employed, it is strongly recommended that collidine is used as the base [4], as this has been shown to significantly reduce loss of optical integrity during coupling.

                  The product number for this product was previously 04-12-1018.

                  To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
                  References
                  Product Information
                  CAS number103213-32-7
                  Hill FormulaC₇H₃₁NO₄S
                  Molar Mass585.73 g/mol
                  HS Code2930 90 19
                  Structure formula ImageStructure formula Image
                  Quality LevelMQ400
                  Applications
                  ApplicationFmoc-Cys(Trt)-OH Novabiochem®. CAS 103213-32-7, molar mass 585.72 g/mol.
                  Biological Information
                  Physicochemical Information
                  Melting Point164 - 175 °C
                  Dimensions
                  Materials Information
                  Toxicological Information
                  Safety Information according to GHS
                  Storage class10 - 13 Other liquids and solids
                  WGKWGK 3 highly hazardous to water
                  Safety Information
                  Product Usage Statements
                  Storage and Shipping Information
                  StorageStore at -15°C to -25°C.
                  Packaging Information
                  Transport Information
                  Supplemental Information
                  Specifications
                  Color (visual)white to off white
                  Appearance of substance (visual)powder
                  Color index (0,5 M in DMF)≤ 150 Hazen
                  Identity (IR)passes test
                  Enantiomeric purity≥ 99.5 % (a/a)
                  Purity (HPLC)≥ 99.0 % (a/a)
                  Fmoc-ß-Ala-OH (HPLC)≤ 0.1 % (a/a)
                  Fmoc-ß-Ala-Cys (Trt) -OH (HPLC)≤ 0.1 % (a/a)
                  Fmoc-Cys(Trt)-Cys(Trt)-OH (HPLC)≤ 0.1 % (a/a)
                  Fmoc-Cys-OH (HPLC)≤ 0.1 % (a/a)
                  Assay free amino acid (HPLC)≤ 0.2 %
                  Purity (TLC(011A))≥ 98 %
                  Purity (TLC(0811))≥ 98 %
                  Solubility (1 mmole in 2 ml DMF)clearly soluble
                  Assay (acidimetric)≥ 98.0 %
                  Water (K. F.)≤ 2.0 %
                  Ethyl acetate (HS-GC)≤ 0.5 %
                  Acetate (IC)≤ 0.02 %
                  For TLC-Systems see our General Catalog
                  Global Trade Item Number
                  Catalogue Number GTIN
                  8520080025 04027269084783
                  8520080100 04027269084790
                  8520080250 04027269206932
                  8520081000 04027269179199

                  Documentation

                  Fmoc-Cys(Trt)-OH SDS

                  Title

                  Safety Data Sheet (SDS) 

                  Citations

                  Title
                  • [1] S. N. McCurdy (1989) Pept. Res., 2, 147.
                  • [2] T. Kaiser, et al. (1996) Tetrahedron Lett., 37, 1187.
                  • [3] Y. X. Han, et al. (1997) J. Org. Chem., 62, 4307.
                  • [4] Y. N. Angell (2002) J. Peptide Res., 5, 292.