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852110 Fmoc-(Dmb)Gly-OH

Fmoc-(Dmb)Gly-OH Novabiochem®. CAS 166881-42-1, molar mass 447.48 g/mol.

Fmoc-(Dmb)Gly-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 166881-42-1 Molar Mass: 447.48 g/mol Hill Formula: C₂₆H₂₅NO₆
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
166881-42-1C₂₆H₂₅NO₆447.48 g/mol

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              Description
              Catalogue Number852110
              Replaces04-12-1268
              Brand Family Novabiochem®
              Alternate Names
              • N-α-Fmoc-N-α-(2, 4-dimethoxybenzyl)-glycine
              Background InformationFmoc-(Dmb)Gly-OH is an excellent reagent for enhancing synthetic efficiency of glycine-containing peptides.

              Like the analogous Hmb derivative Fmoc-(FmocHmb)Gly-OH, the use of this derivative prevents aggregation during chain assemby, thereby leading to faster and more predictable acylation and deprotection reactions. Furthermore, it can prevent aspartimide formation when used to introduce a Gly immediately before an Asp residue and help promote cyclization of Gly-containing peptides [1].

              The analogous (Tmob)Gly derivative has been used by Bayer and colleagues to prepare a 64-residue transmembrane peptide in remarkable purity [2].

              The product number for this product was previously 04-12-1268.

              To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
              References
              Product Information
              CAS number166881-42-1
              Hill FormulaC₂₆H₂₅NO₆
              Molar Mass447.48 g/mol
              Structure formula ImageStructure formula Image
              Quality LevelMQ200
              Applications
              ApplicationFmoc-(Dmb)Gly-OH Novabiochem®. CAS 166881-42-1, molar mass 447.48 g/mol.
              Biological Information
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Storage class10 - 13 Other liquids and solids
              WGKWGK 3 highly hazardous to water
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              StorageStore at -15°C to -25°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Color (visual)white to slight yellow to beige
              Appearance of substance (visual)powder
              Identity (IR)passes test
              Purity (TLC(157B))≥ 98 %
              Assay (HPLC, area%)≥ 99.0 % (a/a)
              Solubility (1 mmole in 2 ml DMF)passes test
              Assay (acidimetric)≥ 94.0 %
              Water (K. F.)≤ 1.00 %
              For TLC-Systems see our General Catalog
              Global Trade Item Number
              Catalogue Number GTIN
              8521100001 04027269089757
              8521100005 04027269089764
              8521109999 04027269089771

              Documentation

              Fmoc-(Dmb)Gly-OH SDS

              Title

              Safety Data Sheet (SDS) 

              Citations

              Title
              • [1] M. El Haddadi, et al. (2000) J. Pept. Sci., 6, 560 (2000) J. Pept. Sci., 6, 560.
              • [2] K. Jauch, et al. in "Peptides 1996: Proc. 24th European Peptide Symposium", R. Ramage and R. Epton (Eds), Mayflower Scientific Ltd., 1996, pp 497.