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852058 Fmoc-Tyr(PO₃H₂)-OH

Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
147762-53-6C₂₄H₂₂NO₈P483.41 g/mol

Pricing & Availability

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      8520580005
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          Description
          Catalogue Number852058
          Replaces04-12-1125
          Brand Family Novabiochem®
          Alternate Names
          • N-α-Fmoc-O-phospho-L-tyrosine
          Background InformationA useful derivative for the synthesis of phosphotyrosine peptides [1-7]. Pyrophosphate formation has been noted in peptides containing adjacent Tyr(PO3H2) residues [4, 5]. An evaluation of the optimal coupling conditions for introduction of this residue has been made [6].

          The product number for this product was previously 04-12-1125.

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          References
          Product Information
          CAS number147762-53-6
          Hill FormulaC₂₄H₂₂NO₈P
          Molar Mass483.41 g/mol
          Structure formula ImageStructure formula Image
          Quality LevelMQ200
          Applications
          ApplicationFmoc-Tyr(PO₃H₂)-OH Novabiochem®. CAS 147762-53-6, molar mass 483.41 g/mol.
          Biological Information
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Storage class10 - 13 Other liquids and solids
          WGKWGK 3 highly hazardous to water
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at -15°C to -25°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Color (visual)white to slight yellow to beige
          Appearance of substance (visual)powder
          Identity (IR)passes test
          Enantiomeric purity≥ 99.5 % (a/a)
          Purity (TLC(CMA1))≥ 95 %
          Purity (TLC(0110))≥ 95 %
          Assay (HPLC, area%)≥ 95.0 % (a/a)
          Solubility (1 mmole in 2 ml DMF)clearly soluble
          Assay (acidimetric)≥ 85.0 %
          Water (K. F.)≤ 2.0 %
          Ethyl acetate (HS-GC)≤ 0.5 %
          Acetate (IC)≤ 0.1 %
          For TLC-Systems see our General Catalog
          Global Trade Item Number
          Catalogue Number GTIN
          8520580001 04027269087609
          8520580005 04027269087616

          Documentation

          Fmoc-Tyr(PO₃H₂)-OH SDS

          Title

          Safety Data Sheet (SDS) 

          Citations

          Title
          • [1] E. A. Ottinger, et al. (1993) Biochemistry, 32, 4354.
          • [2] E. A. Ottinger, et al. (1995) Int. J. Peptide Protein Res., 46, 346.
          • [3] F. Anjuere, et al. (1995) Anal. Biochem., 229, 61.
          • [4] C. Garcia-Echeverria (1995) Lett. Pept. Sci., 2, 93.
          • [5] R. M. Valerio, et al. (1995) Lett. Pept. Sci., 2, 33.
          • [6] C. Garcia-Echeverria (1996) Lett. Pept. Sci., 2, 369.
          • [7] L. F. Bonewald, et al. (1999) J. Peptide Res., 53, 161.