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FCABS165A6 Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate

Milli-Mark Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate detects level of MAPK 1/2 (tERK) & has been published & validated for use in FC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: MAP Kinases Gene Symbol: MAPK1, p38, ERK, P42MAPK, ERK2, p40, PRKM1, p41mapk, PRKM2, MAPK2, p42-MAPK, p41, ERK-2, ERT1 UniProt Number: P21708
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FCABS165A6
100 tests  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFCRbAlexaFluor®647Polyclonal Antibody
      Description
      Catalogue NumberFCABS165A6
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate
      Alternate Names
      • Extracellular signal-regulated kinase 1
      • ERK-1
      • Insulin-stimulated MAP2 kinase
      • Mitogen-activated protein kinase 1
      • MAP kinase 1
      • MAPK 1
      • p44-ERK1
      • ERT2
      • MAP kinase isoform p44
      • p44
      • MAPK
      • Microtubule-associated protein 2 kinase
      • MNK1
      Background InformationThe extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), also called MAPK1 and MAPK2, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. Because the 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade, the two proteins are often referred to collectively as ERK1/2 or MAPK1/2. The MAPK1/2 signaling cascade has been shown to be a critical regulator of cell differentiation, cell physiology and neuronal function. Aberrant control of MAPK1/2 activity has been implicated in a variety of pathological conditions, including cancer and autoimmune diseases, and efficient study methods are in demand.
      References
      Product Information
      FormatAlexaFluor®647
      Control
      • Jurkat cells
      PresentationPurified rabbit polyclonal antibody conjugated to Alexa Fluor 647 in PBS buffer with 15mg/mL BSA and 0.1% Sodium Azide
      Quality LevelMQ100
      Applications
      ApplicationMilli-Mark Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate detects level of MAPK 1/2 (tERK) & has been published & validated for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to rat MAPK 1/2 at the C-terminus.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityAntibody recognizes MAPK1/2. C-terminus.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryKinase involved in intracellular signalling; component of Mapk signalling pathway [RGD]
      Gene Symbol
      • MAPK1
      • p38
      • ERK
      • P42MAPK
      • ERK2
      • p40
      • PRKM1
      • p41mapk
      • PRKM2
      • MAPK2
      • p42-MAPK
      • p41
      • ERK-2
      • ERT1
      Purification MethodProtein A Purfied
      UniProt Number
      UniProt SummaryFUNCTION: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1. Phosphorylates heat shock factor protein 4 (HSF4) By similarity
      Molecular Weight43 kDa Calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using Jurkat cells
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      FCABS165A6 04053252411984

      Documentation

      Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate SDS

      Title

      Safety Data Sheet (SDS) 

      Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate Certificates of Analysis

      TitleLot Number
      Milli-Mark Anti-MAPK 1/2 (tERK), Alexa Fluor#174; 647 Conjugate - 2197289 2197289
      Milli-Mark Anti-MAPK 1/2 (tERK), Alexa Fluor#174; 647 Conjugate - NRG1772829 NRG1772829
      Milli-Mark™ Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate 3063882
      Milli-Mark™ Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate - 3173841 3173841
      Milli-Mark™ Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate - 3981703 3981703
      Milli-Mark™ Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate -2750262 2750262
      Milli-Mark™ Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate - 2420521 2420521

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