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480005 NDSB-201 - CAS 15471-17-7 - Calbiochem

A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Easily removed by dialysis.

NDSB-201 - CAS 15471-17-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 3-(1-Pyridino)-1-propane Sulfonate

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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      15471-17-7C₈H₁₁NO₃S
      Description
      OverviewA non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Easily removed by dialysis.
      Catalogue Number480005
      Brand Family Calbiochem®
      Synonyms3-(1-Pyridino)-1-propane Sulfonate
      References
      ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
      Vuillard, L., et al. 1995. Biochem. J. 305, 337.
      Product Information
      CAS number15471-17-7
      FormWhite powder
      Hill FormulaC₈H₁₁NO₃S
      Chemical formulaC₈H₁₁NO₃S
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥99% by titration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +15°C to +30°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store at room temperature. Stock solutions are stable for up to 3 months at room temperature.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      480005 0

      Documentation

      NDSB-201 - CAS 15471-17-7 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      NDSB-201 - CAS 15471-17-7 - Calbiochem Certificates of Analysis

      TitleLot Number
      480005

      References

      Reference overview
      Goldberg, M.E., et al. 1996. Folding & Design 1, 21.
      Vuillard, L., et al. 1995. Biochem. J. 305, 337.

      Certificates

      Title

      Brochure

      Title
      Biological Detergents Brochure
      Bulk Product Guide

      Citations

      Title
    • Leslie Lobel, et al. (2002) Bacterial expression of a natively folded extracellular domain fusion protein of the hFSH receptor in the cytoplasm of Escherichia coli. Protein Expression and Purification 25, 124-133.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-February-2008 JSW
      Synonyms3-(1-Pyridino)-1-propane Sulfonate
      DescriptionA member of the class of nondetergent sulfobetaines. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range and do not absorb significantly in the near UV range. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis.
      FormWhite powder
      CAS number15471-17-7
      Chemical formulaC₈H₁₁NO₃S
      Structure formulaStructure formula
      Purity≥99% by titration
      SolubilityH₂O (50 mg/ml)
      Storage +15°C to +30°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store at room temperature. Stock solutions are stable for up to 3 months at room temperature.
      Toxicity Irritant
      ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
      Vuillard, L., et al. 1995. Biochem. J. 305, 337.
      Citation
    • Leslie Lobel, et al. (2002) Bacterial expression of a natively folded extracellular domain fusion protein of the hFSH receptor in the cytoplasm of Escherichia coli. Protein Expression and Purification 25, 124-133.
      		•

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Biochemicals > Detergents > Non-Detergent Sulfobetaines