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420355 Isoproterenol, Hydrochloride - CAS 51-30-9 - Calbiochem

Phenethylamine derivative.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Primary Target: β-adrenergic agonist
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420355
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
51-30-9C₁₁H₁₇NO₃ · HCl

Prix & Disponibilité

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420355-100MG
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      Description
      OverviewPhenethylamine derivative. Selective β-adrenergic agonist that stimulates adenylate cyclase activity. Promotes glycogen breakdown and causes bronchodilation. Increases Cl– diffusion and potential difference in rabbit trachea cells through nitric oxide generation. Reported to activate MAP Kinase (ERK) by a Rap1 and B-Raf dependent process.
      Catalogue Number420355
      Brand Family Calbiochem®
      References
      ReferencesSchmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem. 275, 25342.
      Carmena, M.J., et al. 1997. Prostate 33, 46.
      Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
      Kishimoto, I., et al. 1994. J. Biol. Chem. 269, 28300.
      Macaulay, S.L., et al. 1994. Mol. Cell Biochem. 141, 27.
      Yashiro, K., et al. 1994. J. Biochem. 115, 1040.
      Ladenheim, R.G., et al. 1993. J. Neurochem. 60, 260.
      von Zastrow, M., et al. 1993. J. Biol. Chem. 268, 763.
      Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res. 10, 213.
      Product Information
      CAS number51-30-9
      ATP CompetitiveN
      FormWhite to off-white solid
      Hill FormulaC₁₁H₁₇NO₃ · HCl
      Chemical formulaC₁₁H₁₇NO₃ · HCl
      HS Code2918 99 99
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetβ-adrenergic agonist
      Purity≥99% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSDO1925000
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      420355-100MG 04055977187533

      Documentation

      Isoproterenol, Hydrochloride - CAS 51-30-9 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Isoproterenol, Hydrochloride - CAS 51-30-9 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      420355

      Références bibliographiques

      Aperçu de la référence bibliographique
      Schmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem. 275, 25342.
      Carmena, M.J., et al. 1997. Prostate 33, 46.
      Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
      Kishimoto, I., et al. 1994. J. Biol. Chem. 269, 28300.
      Macaulay, S.L., et al. 1994. Mol. Cell Biochem. 141, 27.
      Yashiro, K., et al. 1994. J. Biochem. 115, 1040.
      Ladenheim, R.G., et al. 1993. J. Neurochem. 60, 260.
      von Zastrow, M., et al. 1993. J. Biol. Chem. 268, 763.
      Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res. 10, 213.

      Brochure

      Titre
      Activators and Inhibitors of Adenylate Cyclase Technical Bulletin
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-May-2008 RFH
      DescriptionPhenethylamine derivative. Selective β-adrenergic agonist that increases cytosolic cAMP. Promotes glycogen breakdown and causes bronchodilation. Increases Cl- diffusion and potential difference in rabbit trachea cells through nitric oxide generation.
      FormWhite to off-white solid
      CAS number51-30-9
      RTECSDO1925000
      Chemical formulaC₁₁H₁₇NO₃ · HCl
      Structure formulaStructure formula
      Purity≥99% by TLC
      SolubilityEthanol or H₂O
      Storage Protect from light
      +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Toxicity Irritant
      Merck USA index14, 5217
      ReferencesSchmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem. 275, 25342.
      Carmena, M.J., et al. 1997. Prostate 33, 46.
      Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
      Kishimoto, I., et al. 1994. J. Biol. Chem. 269, 28300.
      Macaulay, S.L., et al. 1994. Mol. Cell Biochem. 141, 27.
      Yashiro, K., et al. 1994. J. Biochem. 115, 1040.
      Ladenheim, R.G., et al. 1993. J. Neurochem. 60, 260.
      von Zastrow, M., et al. 1993. J. Biol. Chem. 268, 763.
      Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res. 10, 213.