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03-0136-00 SMC™ Mouse IL-4 Discovery Immunoassay Kit

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03-0136-00
96 well assay  
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      Analytes AvailableSpecies ReactivityKey Applications
      IL-4 MSingle Molecule Counting (SMC®)
      Description
      Catalogue Number03-0136-00
      Trade Name
      • SMC®
      DescriptionSMC™ Mouse IL-4 Discovery Immunoassay Kit
      OverviewThe SMC™ Mouse IL-4 Discovery Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The SMC™ immunoassay system detects analytes using Single Molecule Counting (SMC™) technology.
      Background InformationInterleukin-4 (IL-4) is a cytokine that is a key regulator in humoral and adaptive immunity. IL-4 induces differentiation of naive helper T-cells (Th0 cells) to Th2 cells. It has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. Further, IL-4 controls the production of IgE, expands IL-4 producing T-cell subsets and stabilizes effector cell functions. IL-4 has great therapeutic potential due to its role in the development of allergic inflammatory responses. IL-4 also has shown to have promise in drug targeting for cancer.
      References
      Product Information
      Components
      • Assay Buffer
      • Mouse IL-4 Coating Antibody
      • Assay Plate
      • 10X PBS
      • Blocking Buffer
      • Standard Diluent
      • Mouse IL-4 Detection Antibody
      • Mouse IL-4 Standard
      • SMC™ Mouse IL-4 Immunoassay Kit Instructions
      • 10X Wash Buffer
      • Buffer C
      • Elution Buffer B
      Precision, %
      • Low-end CV% Range: 0-20%
      • Low-end CV% Average: 4%
      Quality LevelMQ200
      Applications
      ApplicationThe Single Molecule Counting (SMC™) Mouse IL-4 Discovery Immunoassay has unparalleled performance in quantifying IL-4 in mouse serum.
      Key Applications
      • Single Molecule Counting (SMC®)
      Biological Information
      Species Reactivity
      • Mouse
      Analytes Available
      • IL-4
      Accuracy
      • Minimum of 10 samples spiked with acceptable recovery between 80-120%.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size96 well assay
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      03-0136-00 04055977317756

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      Catégories

      Life Science Research > Antibodies and Assays > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits
      Life Science Research > Protein Detection and Quantification > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits