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676950 Veratridine - CAS 71-62-5 - Calbiochem

A Na+ channel opener.

Veratridine - CAS 71-62-5 - Calbiochem : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Primary Target: Na+ channel
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      71-62-5C₃₆H₅₁NO₁₁
      Description
      OverviewA Na+ channel opener. Increases intracellular Ca2+ levels without affecting Na+ - Ca2+ exchange. Acts at neurotoxin receptor site 2 and preferentially binds to activated Na+ channels causing persistent activation. Induces cell death in bovine chromaffin cells.
      Catalogue Number676950
      Brand Family Calbiochem®
      References
      ReferencesMaroto, R., et al. 1994. Eur. J. Pharmacol. 270, 331.
      Plattner, H., et al. 1994. J. Membr. Biol. 142, 229.
      Rando, T.A., et al. 1989. J. Gen. Physiol. 93, 43.
      Rando, T.A., et al. 1986. Mol. Pharmacol. 29, 467.
      Product Information
      CAS number71-62-5
      ATP CompetitiveN
      FormWhite to yellow solid
      Hill FormulaC₃₆H₅₁NO₁₁
      Chemical formulaC₃₆H₅₁NO₁₁
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetNa+ channel
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSYX5600000
      Safety Information
      R PhraseR: 26/27/28

      Very toxic by inhalation, in contact with skin and if swallowed.
      S PhraseS: 26-36/37/39-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      676950 0

      Documentation

      Veratridine - CAS 71-62-5 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Veratridine - CAS 71-62-5 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      676950

      Références bibliographiques

      Aperçu de la référence bibliographique
      Maroto, R., et al. 1994. Eur. J. Pharmacol. 270, 331.
      Plattner, H., et al. 1994. J. Membr. Biol. 142, 229.
      Rando, T.A., et al. 1989. J. Gen. Physiol. 93, 43.
      Rando, T.A., et al. 1986. Mol. Pharmacol. 29, 467.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision22-January-2018 JSW
      DescriptionA Na+ channel opener. Increases intracellular Ca2+ levels without affecting Na+-Ca2+ exchange. Acts at neurotoxin receptor site 2 and preferentially binds to activated Na+ channels causing persistent activation. Induces cell death in bovine chromaffin cells.
      FormWhite to yellow solid
      CAS number71-62-5
      RTECSYX5600000
      Chemical formulaC₃₆H₅₁NO₁₁
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityDMSO (25 mg/ml) or Ethanol (25 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Highly Toxic
      Merck USA index14, 9954
      ReferencesMaroto, R., et al. 1994. Eur. J. Pharmacol. 270, 331.
      Plattner, H., et al. 1994. J. Membr. Biol. 142, 229.
      Rando, T.A., et al. 1989. J. Gen. Physiol. 93, 43.
      Rando, T.A., et al. 1986. Mol. Pharmacol. 29, 467.