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251700 1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride - Calbiochem

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, is an irreversible inhibitor of uPA, Factor Xa & urokinase. Does not inhibit tPA.

MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: 1,5-DNS-GGACK, 2HCl

Primary Target: UPA
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251700
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251700-5MG
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      Description
      OverviewEffective irreversible inhibitor of uPA, Factor Xa, and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Does not inhibit tPA.
      Catalogue Number251700
      Brand Family Calbiochem®
      Synonyms1,5-DNS-GGACK, 2HCl
      References
      ReferencesBajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152.
      Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
      Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
      Product Information
      ATP CompetitiveN
      FormOff-white solid
      ReversibleN
      Quality LevelMQ100
      Applications
      Application1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, is an irreversible inhibitor of uPA, Factor Xa & urokinase. Does not inhibit tPA.
      Biological Information
      Primary TargetUPA
      Primary Target IC<sub>50</sub>100 nM for factor Xa
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      251700-5MG 04055977217957

      Documentation

      1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride - Calbiochem MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride - Calbiochem Certificati d'Analisi

      TitoloNumero di lotto
      251700

      Riferimenti bibliografici

      Panoramica delle referenze
      Bajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152.
      Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
      Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-June-2008 RFH
      Synonyms1,5-DNS-GGACK, 2HCl
      DescriptionEffective irreversible inhibitor of uPA, Factor Xa, and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Does not inhibit tPA.
      FormOff-white solid
      SolubilityReconstitute at 1 mg/ml in 10 mM HCl. Dilute with physiological buffers just prior to use.
      Storage Protect from moisture
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
      Toxicity Standard Handling
      ReferencesBajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152.
      Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
      Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.