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ABC139 Anti-TSPO Antibody

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ABC139
100 µg  
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      Tabella delle specifiche principali

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC139
      ReplacesMABC650
      DescriptionAnti-TSPO Antibody
      Alternate Names
      • Translocator protein
      • Mitochondrial benzodiazepine receptor
      • PKBS
      • Peripheral-type benzodiazepine receptor
      • PBR
      Background InformationTranslocator protein (TSPO) is also called Mitochondrial benzodiazepine receptor, PKBS, or Peripheral-type benzodiazepine receptor (PBR). TSPO generates peripheral-type benzodiazepine recognition sites. TSPO has a role in cholesterol transport across mitochondrial membranes in steroidogenic cells, and may also be involved in in the transport of porphyrins and heme. TSPO is found in many tissue types, but is normally found expressed at the highest levels in steroid synthesizing tissues.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human testis tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-TSPO Antibody is a rabbit polyclonal antibody, validated for use in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blotting Analysis: 1.0 µg/mL from a representative lot detected TSPO in 10 µg of HeLa cell lysate.
      Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected TSPO in human thalamus, human cardiac myocytes and human cerebellum tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human TSPO.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the C-terminus of TSPO.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TSPO
      • BZRP
      • MBR
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~16 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human testis tissue lysate.

      Western Blotting Analysis: 0.25 µg/mL of this antibody detected TSPO in 10 µg of human testis tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      ABC139 04053252915970