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211280 Capsazepine - CAS 138977-28-3 - Calbiochem

A competitive antagonist of Capsaicin and resiniferatoxin. Capsazepine (1 µM) blocks capsaicin (60 nM) stimulated firing of C-fibers.

Capsazepine - CAS 138977-28-3 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide

Primary Target: A competitive antagonist of Capsaicin and resiniferatoxin
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211280
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Tabella delle specifiche principali

CAS #Empirical Formula
138977-28-3C₁₉H₂₁N₂O₂SCl

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211280-10MG
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      Description
      OverviewA competitive antagonist of Capsaicin (Cat. No. 211274) and resiniferatoxin. Capsazepine (1 µM) blocks capsaicin (60 nM) stimulated firing of C-fibers.
      Catalogue Number211280
      Brand Family Calbiochem®
      SynonymsN-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide
      References
      ReferencesFox, A.J., et al. 1995. Neuroscience 67, 741.
      Ellis, J.L., and Undem, B.J. 1994. J. Pharmacol. Exp. Ther. 268, 85.
      Walpole, C.S.J., et al. 1994. J. Med. Chem. 37, 1942.
      Szallasi, A., et al. 1993. J. Pharmacol. Exp. Therap. 267, 728.
      Product Information
      CAS number138977-28-3
      ATP CompetitiveN
      FormOff-white solid
      Hill FormulaC₁₉H₂₁N₂O₂SCl
      Chemical formulaC₁₉H₂₁N₂O₂SCl
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetA competitive antagonist of Capsaicin and resiniferatoxin
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      211280-10MG 04055977219180

      Documentation

      Capsazepine - CAS 138977-28-3 - Calbiochem MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      Capsazepine - CAS 138977-28-3 - Calbiochem Certificati d'Analisi

      TitoloNumero di lotto
      211280

      Riferimenti bibliografici

      Panoramica delle referenze
      Fox, A.J., et al. 1995. Neuroscience 67, 741.
      Ellis, J.L., and Undem, B.J. 1994. J. Pharmacol. Exp. Ther. 268, 85.
      Walpole, C.S.J., et al. 1994. J. Med. Chem. 37, 1942.
      Szallasi, A., et al. 1993. J. Pharmacol. Exp. Therap. 267, 728.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-November 2016 JSW
      SynonymsN-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide
      DescriptionA competitive antagonist of the sensory neuron excitants capsaicin (Cat. No. 211274) and resiniferatoxin (Cat. No. 553975). Capsazepine (1 µM) blocks capsaicin (60 nM) stimulated firing of C-fibers.
      FormOff-white solid
      CAS number138977-28-3
      Chemical formulaC₁₉H₂₁N₂O₂SCl
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO or Methanol
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Toxicity Standard Handling
      ReferencesFox, A.J., et al. 1995. Neuroscience 67, 741.
      Ellis, J.L., and Undem, B.J. 1994. J. Pharmacol. Exp. Ther. 268, 85.
      Walpole, C.S.J., et al. 1994. J. Med. Chem. 37, 1942.
      Szallasi, A., et al. 1993. J. Pharmacol. Exp. Therap. 267, 728.