Millipore Sigma Vibrant Logo

324831 EGF, Human, Recombinant, E. coli

EGF, Human, Recombinant, E. coli: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: Epidermal Growth Factor, Human, Recombinant, E. coli

View Products on Sigmaaldrich.com
324831
Visualizza prezzi e disponibilità

Panoramica

Replacement Information

Tabella delle specifiche principali

Purity
≥95% by SDS-PAGE

Prezzi e disponibilità

Numero di catalogo DisponibilitàConfezionamento Qtà/conf Prezzo Quantità
324831-200UG
Verifica della disponibilità in corso...
—
Disponibilità limitata Disponibilità limitata
A magazzino 
Fuori produzione
Disponibili quantità limitate
La disponibilità deve essere confermata
    Prodotti rimanenti: riceverà un nostro avviso
      Prodotti rimanenti: riceverà un nostro avviso
      Will advise
      Contatti il Servizio Clienti
      Contact Customer Service

      		 Fiala di plastica 200 μg
      Ricerca del prezzo in corso...
      Non è stato possibile trovare il prezzo
      La quantità minima deve essere un multiplo di
      Maximum Quantity is
      Al termine dell'ordine Maggiori informazioni
      Lei ha salvato ()
       
      —
      Richiedi il prezzo
      		 —
      Description
      OverviewRecombinant, human epidermal growth factor (54 amino acids) expressed in E. coli. Identical to human EGF except for an additional N-terminal methionine. Human EGF is 70% homologous to mouse EGF and has been shown to have similar biological activity. Mitogenic for a wide range of ectoderm- and endoderm-derived cells from tissue such as breast, cornea, epidermis, dermis, liver, pancreas, nerve, amnion, and adrenal medulla. Acts as a survival factor in preventing apoptosis.
      Catalogue Number324831
      Brand Family Calbiochem®
      SynonymsEpidermal Growth Factor, Human, Recombinant, E. coli
      References
      ReferencesMerlo, G.R., et al. 1995. J. Cell Biol. 128, 1185.
      Yoshida, T., et al. 1993. Brain Res. Dev. 76, 147.
      Rubin, J.S., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 415.
      Carpenter, G., and Wahl, M.I. 1990. In The Epidermal Growth Factor Family in Peptide Growth Factors and Their Receptors (Sporn, M.B., and Roberts, A.B., eds.) Springer-Verlag, New York, p 69.
      Downward, J., et al. 1984. Nature 311, 483.
      Gray, A., et al. 1983. Nature 303, 722.
      Scott, J., et al. 1983. Science 221, 236.
      Cohen, S. 1960. Proc. Natl. Acad. Sci. USA 46, 302.
      Product Information
      CAS number62229-50-9
      FormSolid
      FormulationLyophilized from sterile-filtered PBS.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ = 100-400 pg/ml as measured by its ability to stimulate the ³H-thymidine incorporation in an EGF-responsive mouse fibroblast cell line, Balb/3T3.
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: <1.0 EU/μg EGF
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSKB4518000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C) for long term storage or refrigerate (4°C) for short-term storage. Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C or -70°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      324831-200UG 04055977216189

      Documentation

      EGF, Human, Recombinant, E. coli MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      EGF, Human, Recombinant, E. coli Certificati d'Analisi

      TitoloNumero di lotto
      324831

      Riferimenti bibliografici

      Panoramica delle referenze
      Merlo, G.R., et al. 1995. J. Cell Biol. 128, 1185.
      Yoshida, T., et al. 1993. Brain Res. Dev. 76, 147.
      Rubin, J.S., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 415.
      Carpenter, G., and Wahl, M.I. 1990. In The Epidermal Growth Factor Family in Peptide Growth Factors and Their Receptors (Sporn, M.B., and Roberts, A.B., eds.) Springer-Verlag, New York, p 69.
      Downward, J., et al. 1984. Nature 311, 483.
      Gray, A., et al. 1983. Nature 303, 722.
      Scott, J., et al. 1983. Science 221, 236.
      Cohen, S. 1960. Proc. Natl. Acad. Sci. USA 46, 302.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-May-2008 RFH
      SynonymsEpidermal Growth Factor, Human, Recombinant, E. coli
      DescriptionRecombinant, human epidermal growth factor (54 amino acids) expressed in E. coli. Identical to native human EGF except for an additional N-terminal methionine. Human EGF is 70% homologous to mouse EGF and has been shown to have similar biological activity. Mitogenic for a wide range of ectoderm- and endoderm-derived cells from tissue such as breast, cornea, epidermis, dermis, liver, pancreas, nerve, amnion, and adrenal medulla. Binding of EGF to its 170 kDa transmembrane receptor results in dimerization of the receptor, activation of the intrinsic receptor tyrosine kinase, and initiation of the complex signal transduction cascade that leads to cell proliferation and/or differentiation. Acts as a survival factor in preventing apoptosis.
      FormSolid
      FormulationLyophilized from sterile-filtered PBS.
      CAS number62229-50-9
      RTECSKB4518000
      Purity≥95% by SDS-PAGE
      ContaminantsEndotoxin: <1.0 EU/μg EGF
      Biological activityED₅₀ = 100-400 pg/ml as measured by its ability to stimulate the ³H-thymidine incorporation in an EGF-responsive mouse fibroblast cell line, Balb/3T3.
      SolubilityReconstitute to a concentration of ≥10 µg/ml in 10 mM acetic acid containing ≥0.1% HSA or BSA.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C) for long term storage or refrigerate (4°C) for short-term storage. Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C or -70°C.
      Toxicity Standard Handling
      Merck USA index14, 3527
      ReferencesMerlo, G.R., et al. 1995. J. Cell Biol. 128, 1185.
      Yoshida, T., et al. 1993. Brain Res. Dev. 76, 147.
      Rubin, J.S., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 415.
      Carpenter, G., and Wahl, M.I. 1990. In The Epidermal Growth Factor Family in Peptide Growth Factors and Their Receptors (Sporn, M.B., and Roberts, A.B., eds.) Springer-Verlag, New York, p 69.
      Downward, J., et al. 1984. Nature 311, 483.
      Gray, A., et al. 1983. Nature 303, 722.
      Scott, J., et al. 1983. Science 221, 236.
      Cohen, S. 1960. Proc. Natl. Acad. Sci. USA 46, 302.