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344932 Furin, Human, Recombinant

Furin, Human, Recombinant: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
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344932
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Replacement Information

Prezzi e disponibilità

Numero di catalogo DisponibilitàConfezionamento Qtà/conf Prezzo Quantità
344932-50UL
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      Description
      OverviewRecombinant, human furin expressed in vaccinia virus (VV:hFUR713t) infected BSC-40 cells. Supplied as a crude preparation of soluble furin obtained from cytoplasmic extracts. Furin is a type I membrane protein that processes stromelysin-3 (MMP-11) and MT1-MMP. It cleaves pro-hormones, neuropeptide precursors, some viral proteins, and bacterial toxins.
      This preparation was subjected to UV irradiation for 5 min to inactivate any residual vaccinia virus.
      Catalogue Number344932
      Brand Family Calbiochem®
      References
      ReferencesBassi, D.E., et al. 2001. Mol. Carcinog. 31, 224.
      Bassi, D.E., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 10326.
      Creemers, J.W., et al. 2001. J. Biol. Chem. 276, 4211.
      Wang, X., and Pei, D. 2001. J. Biol. Chem. 276, 35953.
      Molloy, S.S., et al. 1992. J. Biol. Chem. 267, 16396.
      Product Information
      Unit of DefinitionOne unit is defined as the amount of furin that will cleave 1.0 pmol AMC from the substrate pGlu-Arg-Thr-Lys-Arg-AMC per min at 30°C, pH 7.5.
      FormLiquid
      FormulationIn 20 mM Bis-Tris buffer, 1 mg/ml BSA, pH 7.0.
      Quality LevelMQ100
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      344932-50UL 04055977194401

      Documentation

      Furin, Human, Recombinant MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      Furin, Human, Recombinant Certificati d'Analisi

      TitoloNumero di lotto
      344932

      Riferimenti bibliografici

      Panoramica delle referenze
      Bassi, D.E., et al. 2001. Mol. Carcinog. 31, 224.
      Bassi, D.E., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 10326.
      Creemers, J.W., et al. 2001. J. Biol. Chem. 276, 4211.
      Wang, X., and Pei, D. 2001. J. Biol. Chem. 276, 35953.
      Molloy, S.S., et al. 1992. J. Biol. Chem. 267, 16396.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision21-January-2008 JSW
      DescriptionRecombinant, human furin expressed in vaccinia virus (VV:hFUR713t) infected BSC-40 cells. Furin is a membrane-associated, calcium-dependent, serine protease that belongs to the subtilisin-like pro-hormone convertase (PC) family. Members of this family cleave pro-hormones, neuropeptide precursors, some viral proteins, and bacterial toxins. The preparation was subjected to UV irradiation for 5 minutes to inactivate any residual virus.
      FormLiquid
      FormulationIn 20 mM Bis-Tris buffer, 1 mg/ml BSA, pH 7.0.
      Unit definitionOne unit is defined as the amount of furin that will cleave 1.0 pmol AMC from the substrate pGlu-Arg-Thr-Lys-Arg-AMC per min at 30°C, pH 7.5.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesBassi, D.E., et al. 2001. Mol. Carcinog. 31, 224.
      Bassi, D.E., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 10326.
      Creemers, J.W., et al. 2001. J. Biol. Chem. 276, 4211.
      Wang, X., and Pei, D. 2001. J. Biol. Chem. 276, 35953.
      Molloy, S.S., et al. 1992. J. Biol. Chem. 267, 16396.