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Histones and Histone Modifications | Life Science Research | Merck
Histone modifications regulate DNA transcription, repair, recombination, and replication, and can alter local chromatin architecture. Understanding histone modifications is key to uncovering epigenetic mechanisms of gene regulation. Merck grasps the complexity of this research and provides a growing line of kits, antibodies, and assays for studying histones and their modifications. Merck offers over 600 validated antibodies, recombinant proteins, and kits to analyze histone and histone-variant phosphorylation, methylation, acetylation, ubiquitination, and citrullination-the most widely studied histone modifications in epigenetics today. -
TLC Tips and Tricks | Merck
Get practical TLC tips about: choice of solvent and layer, pre-conditioning, sample position, drying, chamber saturation, spraying and TLC scanners. -
Glycosylated Amino Acids | Reagents, Chemicals and Labware | Merck
Merck's range for the highly quality glycosylated amino acids for glycopeptide synthesis. -
Strat-M® Membrane Compound Data | Life Science Research | Merck
Strat-M membrane provides you with compound data to predict transdermal diffusion of a variety of compounds. -
LiChrospher® RP-18 (5 µm) | Analytical and Sample Preparation | Merck
LiChrospher® RP-18 (5 µm) columns for reversed-phase HPLC are classified as L1 columns, fully compliant with US Pharmacopoeia specifications. -
LiChrospher® 100 RP-18 and RP-18 Endcapped | Analytics and Sample Preparation | Merck
LiChrospher® 100 RP-18 and RP-18 endcapped columns offer very high reliability for reversed-phase HPLC of acidic, neutral and weakly basic compounds. -
ChIP Kits | Life Science Research | Merck
ChIP kits selection guide provides you with more information and details about each type of ChiPs : Description, Number of assays, Assay time, Availability with protein A or G, Agarose or Magnetic, etc.. -
Histone Peptide Arrays | Life Science Research | Merck
Histone peptide arrays are essential screening tools to evaluate the specificity and cross-reactivity of antibodies against histones H2A, H2B, H3, H4, and their post-translational modifications.The arrays are designed on PVDF membranes for a simple Western blot-like assay. -
Other Inhibitors and Small Molecules | Life Science Research | Merck
We provide other inhibitors including FTase, GGTase and methyltransferase inhibitors, glycoprotein processing and trafficking, and more for specific research areas.