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253300 Deltamethrin - CAS 52918-63-5 - Calbiochem

Deltamethrin, CAS 52918-63-5, is a synthetic type II pyrethroid that acts as a potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 100 pM).

Deltamethrin - CAS 52918-63-5 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (S)-α-Cyano-3-phenoxybenzyl(1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate

Primary Target: protein phosphatase 2B
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
52918-63-5C₂₂H₁₉Br₂NO₃

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253300-10MG
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      Description
      OverviewSynthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 100 pM). May also have varied effects on ion channels. Causes an increase in neurotransmitter release at synapses, and increases intrasynaptosomal Ca2+ levels.
      Catalogue Number253300
      Brand Family Calbiochem®
      Synonyms(S)-α-Cyano-3-phenoxybenzyl(1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate
      References
      ReferencesRichter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
      Enan, E., and Matsumura, F. 1993. Biochem. Pharmacol. 45, 703.
      Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
      Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.
      Product Information
      CAS number52918-63-5
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₂₂H₁₉Br₂NO₃
      Chemical formulaC₂₂H₁₉Br₂NO₃
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationDeltamethrin, CAS 52918-63-5, is a synthetic type II pyrethroid that acts as a potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 100 pM).
      Biological Information
      Primary Targetprotein phosphatase 2B
      Primary Target IC<sub>50</sub>100 pM against calcineurin (protein phosphatase 2B)
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSGZ1233000
      Safety Information
      R PhraseR: 21-23-28

      Harmful in contact with skin.
      Toxic by inhalation.
      Very toxic if swallowed.
      S PhraseS: 26-36/37/39-45-53

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Avoid exposure - obtain special instructions before use.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid acid or alkali conditions.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      253300-10MG 04055977217391

      Documentation

      Deltamethrin - CAS 52918-63-5 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Deltamethrin - CAS 52918-63-5 - Calbiochem Certificates of Analysis

      TitleLot Number
      253300

      References

      Reference overview
      Richter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
      Enan, E., and Matsumura, F. 1993. Biochem. Pharmacol. 45, 703.
      Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
      Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-December-2007 JSW
      Synonyms(S)-α-Cyano-3-phenoxybenzyl(1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate
      DescriptionSynthetic type II pyrethroid insecticide. Potent inhibitor of calcineurin (protein phosphatase 2B, IC50 = 100 pM). May also have varied effects on ion channels. Causes an increase in neurotransmitter release at synapses and also increases intrasynaptosomal Ca2+ levels.
      FormWhite solid
      CAS number52918-63-5
      RTECSGZ1233000
      Chemical formulaC₂₂H₁₉Br₂NO₃
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityDMSO (15 mg/ml) or Ethanol (1 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid acid or alkali conditions.
      Toxicity Highly Toxic
      Merck USA index14, 2883
      ReferencesRichter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
      Enan, E., and Matsumura, F. 1993. Biochem. Pharmacol. 45, 703.
      Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
      Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.