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EZHFGF21-19K Human FGF-21 ELISA Kit

This Human FGF-21 ELISA Kit is used to measure & quantify FGF-21 levels in Metabolism & Inflammation & Immunology research.

Human FGF-21 ELISA Kit MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: ELISA Detection Methods: Fluorescent, Colorimetric Research Category: Metabolism Research Sub-Category: Diabetes - Type 2, Metabolic Syndrome
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EZHFGF21-19K
96-well strip plate  
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      Overview

      Replacement Information

      Key Spec Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      FGF-21 HELISAFluorescent Colorimetric
      Description
      Catalogue NumberEZHFGF21-19K
      DescriptionHuman FGF-21 ELISA Kit
      Background InformationRecent studies have demonstrated that fibroblast growth factor 21 (FGF-21), a liver derived protein, is able to increase glucose uptake, as well as lower plasma triglyceride levels in an insulin-independent manner. FGF-21 suppresses glucagon release, thereby increasing insulin sensitivity, and reduces the amount of insulin production required by pancreatic β-cells. Unlike insulin, which works in a rapid, hormone-like manner, FGF-21 activity requires several hours, indicating changes in gene expression. While insulin functions through GLUT4 translocation, FGF-21 has been shown to act primarily through the upregulation of adipocyte GLUT1, a transporter that allows glucose to move from the blood into cells even in the absence of insulin. In addition, no significant weight gain was observed when FGF-21 was injected into animals, and mice that had been genetically engineered to overexpress FGF-21 weighed less and had less adipose tissue than the normal controls.
      References
      Product Information
      Detection methodFluorescent Colorimetric
      Precision, %
      • Intra-assay: < 6%
      • Inter-assay: < 9%
      Quality LevelMQ200
      Applications
      ApplicationThis Human FGF-21 ELISA Kit is used to measure & quantify FGF-21 levels in Metabolism & Inflammation & Immunology research.
      Key Applications
      • ELISA
      Application NotesThis is a 3-hour assay requiring 50 μL of sample.
      Biological Information
      SpecificityNo significant cross-reactivity to the cytokines and metabolic hormones tested was observed.
      Species Reactivity
      • Human
      Analytes Available
      • FGF-21
      Accuracy
      • 83 – 99%
      Physicochemical Information
      Linearity of DilutionPlease contact Technical Service for this information
      Standard Curve Range
      • 31.3– 2000 pg/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • For research use only. Not for use in diagnostic procedures.
      Storage and Shipping Information
      Packaging Information
      Material Size96-well strip plate
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      EZHFGF21-19K 04053252511073

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      Categories

      Life Science Research > Antibodies and Assays > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits
      Life Science Research > Protein Detection and Quantification > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits