MultiScreen® Plate Overview
 
MultiScreen® plates are proven as optimized, reliable tools for the advancement of drug discovery and life science research.
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MultiScreen® plates are proven as optimized, reliable tools for the advancement of drug discovery and life science research. Less
 
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Overview
Specifications
Ordering Information
Documentation
References
| Reference overview | Application | 
|---|---|
| Supercritical fluid chromatography-tandem mass spectrometry for fast bioanalysis of R/S-warfarin in human plasma Roger A. Coe, Jonathan O. Rathe, and Jean W. Lee; Journal of Pharmaceutical and Biomedical Analysis, 42 (2006) 573-580 Journal of Pharmaceutical and Biomedical Analysis, 42 (2006) 573-580 2006 | Chromatography, Mass Spectrometry Sample Prep | 
| 96-well chromatography with the Multiscreen(R) Assay System Diehl P; Scientist, 1998, v12, n14 (Jul. 6), p17-17 Scientist, 1998, v12, n14 (Jul. 6), p17-17 1998 | Chromatography | 
| A 96-Well Plate Protein Assay for Samples Containing Sodium Dodecyl Sulfare and Reducing Agent Using the Multiscreen Nitrocellulose Filtration Plaste with Amido Black Mahoney, C.W., Nakanishi, N., and Ohashi, M.A; Analytical BioChemistry, 248:182-184. 1997 Analytical BioChemistry, 248:182-184. 1997 1997 | Sample Prep | 
Related Products & Applications
Product Families
|   
 MultiScreen Plates and Millicell Inserts with Polycarbonate and PET membranesThe Isopore membrane is a polycarbonate, track-etched screen filter recommended for all analyses in which the sample is viewed on the surface of the membrane.Learn More >> | 
|   
 MultiScreen® Filter Plates with Durapore® MembraneThese Multiscreen filter plates offer High-throughput filtration with low protein bindingLearn More >> | 
|   
 MultiScreen plates with specialty membranesMultiScreen plates are available with a variety of specialty membranes for different applications.Learn More >> | 
|   
 MultiScreen plates and Millicell Inserts with MCE membraneUsed for Elispot assays, bacterial screening, ELISA or viral infection studiesLearn More >> | 
|   
 Cell Cultureware and AccessoriesPre-coated ECM multiwell plates in multiple formats including Collagen, and Fibronectin.Learn More >> | 
|   
 MultiScreen® Filter Plates with Glass Fiber FiltersHigh-throughput clarification and prefiltrationLearn More >> | 
Related Products By: Application Facete
| Protein Purification | 
| Sample Preparation | 
| Dialysis and Filtration | 
Related Products By: Brand Facete
| MultiScreen™ | 
Categories
| Life Science Research > Cell Culture and Systems > Cell Culture Flasks, Plates, & Slides > Multiwell Plates | 
No matter what application you’re working with, Millipore has a plate developed to meet your specific needs. MultiScreen plates have a long history as a reliable tool for the advancement of drug discovery and life science research. 
The table below lists dozens of different uses for MultiScreen platforms, including bead-based assays, bioassays, sample preparation, cell harvesting, cell culture, and ADME assays. Our expanded line of membrane-based solutions includes MultiScreenHTS 96- and 384-well filter plates, as well as MultiScreen Deep Well filter plates. For a full list of products see the table below.
HTS Filter Plates
MultiScreenHTS plates are specifically developed for high-throughput use with automated work stations. Rigid sidewalls improve handling and ample surfaces are provided for bar code labels. Wells are individually sealed to prevent incubation crosstalk and the underdrain is removable for access to the filters. Filter plates are available in 96- and 384-well platforms with a broad selection of membranes and plastics. 
Millipore’s new MultiScreen HTS+ Hi flow filter plate design lessens non-specific binding and reduces variability in both background and signal intensities specifically for biochemical screening assays.
Classic Filter Plates
The original multiwell design is valuable for many applications which require immersing the filter in an assay tray. The easily removable underdrain and unique plate design are ideal for assays such as Elispot, PAMPA, cell screening (migration, invasion or chemotaxis) or for topcount detection users.
Accessory – MultiScreenHTS Vacuum Manifold
The MultiScreenHTS Vacuum manifold was designed specifically to work with MultiScreenHTS filter plates. The combination results in optimal filtration characteristics and seamless automation integration.
Millicell Assay Plates
In addition to the traditional assay plate format, filter plates are also available with cell culture trays for growing and assaying suspension and adherent cell lines. Cells grown on filter plates differentiate better than those grown on traditional plastic substrates, resulting in more in vivo-like results This filter plate/tray combination can be used for a variety of cellular assays, including, transport, toxicity and screening assays.
| Membrane Type | Durapore® (PVDF) | MCE (Mixed cellulose ester) | Immobilon-P (PVDF) | PTFE | Isopore™ (Polycarbonate) | Specialty Membranes | Ultracel®-10 (ultrafiltration) | 
| Common applications | Sample prep DNA binding Clinical diagnostics Protein kinase | Elispot | Elispot DNA binding Protein binding Lipid kinase assay | Total drug analysis Solubility testing In-plate protein precipitation | Cell growth Caco assay Epithelial Cell Culture Solubility testing Migration, Invasion, Chemotaxis assay | Receptor biding assyas Protein kinase assay DNA purification Cell Harvesting assay | PCR purification Sequencing reaction purification Plasmid/BAC purification | 
| Membrane characteristics | Low protein/nucleic acid binding | High protein/nucleic acid binding | High protein/nucleic acid binding | Organic Solvent Resistant | translucent for visualization | glass fiber, paper | Size exclusion | 
| Pore sizes | 0.22–1.2µm | 0.45µm | 0.45µm | 0.45µm | 0.4–8.0µm | ||
| Hydrophilic/ Hydrophobic | both | philic | phobic | both | philic | philic | philic | 
| Sterile/Non-sterile | both | both | both | non-sterile | both | non-sterile | non-sterile | 
| Plate color | Clear White Opaque | Clear Opaque | Styrene Barex Acrylic | Solvent Resistant Clear | Clear | Opaque | Clear | 

 


 
  

 
 
 
 
