Agonist
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239824 Sigma-AldrichCXCR7 Agonist, VUF11207 - CAS 1378524-41-4 - Calbiochem
CXCR7 Agonist, VUF11207, CAS 1378524-41-4, is a high affinity and high potency ligand of CXCR7 (pKi = 8.1). Induces the recruitment of β-arrestin2 and subsequent interenalization of CXCR7.
530533 Sigma-AldrichTRPV4 Agonist, GSK1016790A - CAS 942206-85-1 - Calbiochem
A cell-permeable, potent, selective agonist of TRPV4 channel. Enhances Ca2+ flux in a variety of human and mouse cells (EC₅₀ = 2.1 nM for human TRPV4).
371721 Sigma-AldrichGPR40 Agonist II - CAS 1206629-08-4 - Calbiochem
The GPR40 Agonist II controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Biochemicals applications.
371706 Sigma-AldrichGPR40 Agonist - CAS 885101-89-3 - Calbiochem
The GPR40 Agonist, also referenced under CAS 885101-89-3, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Cell Signaling applications.
566660 Sigma-AldrichSmoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem
A cell-permeable Smoothened Agonist, SAG, CAS 364590-63-6, modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (KD = 59 nM).
553030 Sigma-AldrichRAGE Antagonist, FPS-ZM1 - CAS 945714-67-0 - Calbiochem
RAGE Antagonist, FPS-ZM1, is a blood-brain-barrier permeant blocker of RAGE V domain-mediated ligand binding (Ki = 25, 148, & 230 nM, respectively, against Aβ40, HMGB1 & S100B, binding to sRAGE).
371830 Sigma-AldrichGPR40 Antagonist, GW1100 - CAS 306974-70-9 - Calbiochem
The GPR40 Antagonist, GW1100, also referenced under CAS 306974-70-9, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Biochemicals applications.
373400 Sigma-AldrichHh/Gli Antagonist, GANT58 - CAS 64048-12-0 - Calbiochem
The Hh/Gli Antagonist, GANT58, also referenced under CAS 64048-12-0, controls the biological activity of Hh/Gli. This small molecule/inhibitor is primarily used for Cell Signaling applications.
654255 Sigma-AldrichTNF-α Antagonist - Calbiochem
The TNF-α Antagonist controls the biological activity of TNF-α.