MISSION® esiRNA

MISSION® esiRNA—powered by Eupheria Biotech—provides RNAi researchers with a proven, cost-effective, and simple way to perform post-transcriptional silencing of protein-coding genes and lncRNA (long non-coding RNA). Biologically-prepared esiRNA are comprised of a heterogeneous pool of siRNA (natural RNA, no modifications) that all target the same mRNA sequence. These multiple silencing triggers lead to highly specific and effective gene knockdowns with lower off-target effects than single, chemically-synthesized siRNA.
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Related resources
- Article: MISSION® esiRNA specifications
MISSION® esiRNA provides RNAi researchers with a proven, cost-effective, and simple way to perform RNAi screens.
- Article: esiRNA FAQs (Frequently asked questions)
esiRNA are endoribonuclease prepared siRNAs that target the same mRNA sequence for gene silencing. Here are some of the most asked questions regarding esiRNA uses and availability.
- Article: Custom oligos and qPCR probes online tools
Learn more about the tools we offer for oligo and qpcr probe design, including OligoArchitect™ Primer and Probe Design Solutions and OligoEvaluator™: Oligonucleotide Sequence Calculator.
- Article: Custom DNA/RNA oligos and qPCR probes resources
Review resources for custom oligos, RNA oligos, and qPCR probes including online tools, case studies, and FAQs.
- Article: Oligo product reviews by SelectScience®
Custom & oredesigned DNA Oligos peer reviews. Check out what your peers are saying!
- Custom siRNA
RNA interference via siRNA offers precise gene silencing, aiding gene function studies and drug target screening.
- Predesigned siRNA
Rosetta siRNA Design Algorithm optimizes siRNA sequences for reduced off-target effects and increased RNAi performance.
- MISSION® Lentiviral shRNA
MISSION shRNA reduce the expression of specific target genes by targeting the specific mRNA therefore reducing the corresponding protein expression.
- siRNA Universal Neg. Controls
MISSION siRNA Negative Controls ensure mRNA knockdown efficiency baseline; tested in human, rat, and mouse cells, designed without gene homology.