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MABN743 Anti-CALCRL Antibody, clone 9G2.1

MABN743
100 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN743
DescriptionAnti-CALCRL Antibody, clone 9G2.1
Alternate Names
  • calcitonin receptor-like receptor
  • CALCRL
  • Calcitonin gene-related peptide type 1 receptor
  • CGRP type 1 receptor
  • CRLR
Background InformationCALCRL is the cell membrane receptor for the calcitonin-gene-related peptide (CGRP) together with RAMP1 (receptor activity modifying protein 1). CALCRL is also the adrenomedullin receptor but only in association with RAMP3. RAMPs are required to transport calcitonin-receptor-like receptor (CALCRL) to the plasma membrane. The CALCRL associated receptors are G-protein coupled receptors expressed in the lung and heart tissues.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-CALCRL Antibody, clone 9G2.1 is an antibody against CALCRL for use in Immunohistochemistry and Immunocytochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blotting Analysis: 0.5 µg/mL from a representative lot detected CALCRL in 10 µg of mouse brain, mouse cerebellum, mouse hypothalamus, and human pituitary tissue lysate.
Immunohistochemistry Analysis: A 1:50-250 dilution from a representative lot detected CALCRL in human lung and human heart tissue.
Biological Information
ImmunogenLinear peptide corresponding to human CALCRL.
Clone9G2.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • CALCRL
  • CGRPR
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~55 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human lung tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected CALCRL in 10 µg of human lung tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN743 04055977136333