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MABT200 Anti-COL1A2, clone alpha2CT, Azide Free Antibody

MABT200
100 µg  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HIHC, ACTMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABT200
DescriptionAnti-COL1A2, clone alpha2CT, Azide Free Antibody
Alternate Names
  • Annexin A6
  • 67 kDa calelectrin
  • Annexin VI
  • Annexin-6
  • Calphobindin-II
  • CPB-II
  • Lipocortin VI
  • Protein III
  • p68
  • p70
Background InformationCollagens are major fibrous structural elements of cartilage, tendon, bone, skin, lung, and blood vessels. Type I collagen, a heterotrimer consisting of two α1 chains and one α2 chain, is the most abundant fibrillar collagen. It is preferentially synthesized in bone, skin, and tendon and is the most abundant protein found in these tissues.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgAκ in buffer containing PBS without preservatives.
Quality LevelMQ100
Applications
ApplicationAnti-COL1A2 antibody, clone alpha2CT, Azide Free is an antibody against COL1A2 for use in IHC & activity assay.
Key Applications
  • Immunohistochemistry
  • Activity Assay
Application NotesActivity Assay Analysis: A representative lot from an independent laboratory inhibits fibrin formation in vitro (Chung, H. J., et al. (2008). J Biol Chem. 283(38):25879-25886.).
Biological Information
ImmunogenLinear peptide corresponding to the C-terminus of human Collagen type I alpha 2.
EpitopeC-terminus
Clonealpha2CT
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgAκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • ANXA6
  • ANX6
Purification MethodProtein L
UniProt Number
Molecular Weight125 and 150 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunohistochemistry Analysis in human bone tissues.

Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected COL1A2 in human bone tissues.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABT200 04053252947087

Documentation

Anti-COL1A2, clone alpha2CT, Azide Free Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-COL1A2, clone alpha2CT, Azide Free Antibody Certificates of Analysis

TitleLot Number
Anti-COL1A2, clone alpha2CT, Azide Free - 3324203 3324203
Anti-COL1A2, clone alpha2CT, Azide Free - Q2366202 Q2366202

References

Reference overviewPub Med ID
Collagen fibril formation. A new target to limit fibrosis.
Chung, Hye Jin, et al.
J. Biol. Chem., 283: 25879-86 (2008)  2008

Show Abstract
18650436 18650436