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ABN201 Anti-CYP24A1 Antibody

Anti-CYP24A1 Antibody is an antibody against CYP24A1 for use in 0.

Anti-CYP24A1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: CYP24A1, CYP24 UniProt Number: Q07973
ABN201
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN201
DescriptionAnti-CYP24A1 Antibody
Alternate Names
  • 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
  • 24-OHase
  • Vitamin D(3) 24-hydroxylase
  • Cytochrome P450 24A1
  • Cytochrome P450-CC24
Background InformationAlso known as Vitamin D(3) 24-hydroxylase, CYP24A1 is a member of the cytochrome P450 (CYP) family of enzymes. Most members of the CYP family can metabolize multiple substrates, and can catalyze multiple reactions. The CYP24A1 is a mitochondrial protein that starts the breakdown of 1,25-dihydrozyvitamin D3 by hydroxylation of the side chain to form calcitroic acid. This enzyme also has a role in calcium homeostasis and the vitamin D endocrine system.
References
Product Information
FormatAffinity Purified
Control
  • A549 cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-CYP24A1 Antibody is an antibody against CYP24A1 for use in 0.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human CYP24A1.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
Species Reactivity NoteDemonstrated to react with Human. Other Homologies: Bovine (92% sequence homology) and Rat (75% sequence homology).
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • CYP24A1
  • CYP24
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~60 kDa observed. Two isoforms are known to exist at 59 kDa and 51 kDa. This antibody is expected to recognize both isoforms.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in A549 cell lysate.

Western Blot Analysis: 0.2 µg/mL of this antibody detected CYP24A1 in 10 µg of A549 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABN201 04053252826030