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ABC100 Anti-Hyaluronan synthase 3 Antibody

Detect Hyaluronan synthase 3 using this Anti-Hyaluronan synthase 3 Antibody validated for use in Western Blotting & IHC.

Anti-Hyaluronan synthase 3 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: HAS3 UniProt Number: O00219
ABC100
100 µg  
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Overview

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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC100
DescriptionAnti-Hyaluronan synthase 3 Antibody
Alternate Names
  • Hyaluronan synthase 3
  • Hyaluronate synthase 3
  • Hyaluronic acid synthase 3
  • HA synthase 3
Background InformationHyaluronan synthase 3 (HAS3) is one of three enzymes, located at the plasma membrane, that synthesizes the glycosaminoglycan hyaluronan. Hyaluronan is involved in cell proliferation, differentiation, angiogenesis, and tumor development, among other cellular processes. Hyaluronan synthase 3 creates the low—molecular-weight hyaluronan, whereas hyaluronan synthase 1 and 2 create high molecular weight isoforms.
References
Product Information
FormatAffinity Purified
Control
  • SW620 cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Hyaluronan synthase 3 using this Anti-Hyaluronan synthase 3 Antibody validated for use in Western Blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:500-1,000 dilution from a representative lot detected Hyaluronan synthase 3 in human liver and human kidney tissues.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Hyaluronan synthase 3.
EpitopeCytoplasmic domain
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes both isoforms at the cytoplasmic domain of Hyaluronan synthase 3.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • HAS3
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~28/60 kDa observed. An uncharacterized band appears at ~70 kDa in some lysates. The calculated molecular weight of this protein is 63 kDa for isoform 1 and 31 kDa for isoform 2, but can be observed at ~60 and ~28 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in SW620 cell lysate.

Western Blot Analysis: 2 µg/mL of this antibody detected Hyaluronan synthase 3 on 10 µg of SW620 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABC100 04053252441455

Documentation

Anti-Hyaluronan synthase 3 Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-Hyaluronan synthase 3 Antibody Certificates of Analysis

TitleLot Number
Anti-Hyaluronan synthase 3 - 2495487 2495487
Anti-Hyaluronan synthase 3 - 2564038 2564038
Anti-Hyaluronan synthase 3 - Q2030495 Q2030495
Anti-Hyaluronan synthase 3 -2618512 2618512
Anti-Hyaluronan synthase 3 Polyclonal Antibody 2949137

References

Reference overviewPub Med ID
Cytotoxic diterpenoids from Isodon enanderianus.
Xiang, Wei, et al.
Planta Med., 69: 1031-5 (2003)  2003

Show Abstract 		14735442 14735442