Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

MABN1176 Anti-MAPK10, clone 10E4A4 Antibody

Anti-MAPK10, clone 10E4A4 Antibody is an antibody against MAPK10 for use in Immunocytochemistry.

Anti-MAPK10, clone 10E4A4 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: MAPK10, JNK3, JNK3A, PRKM10, SAPK1B UniProt Number: P53779
MABN1176
100 µL  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HICCMAscitesMonoclonal Antibody
Description
Catalogue NumberMABN1176
Replaces05-893
DescriptionAnti-MAPK10, clone 10E4A4 Antibody
Alternate Names
  • Mitogen-activated protein kinase 10
  • MAP kinase 10
  • MAPK 10
  • MAPK10
Background Informationmitogen-activated protein kinase 10 (MAPK10), also known as JNK3, JNK3A, PRKM10, p54bSAPK, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. MAPK10 is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.
References
Product Information
FormatAscites
PresentationMouse monoclonal IgG1ascitic fluid containing 0.03% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-MAPK10, clone 10E4A4 Antibody is an antibody against MAPK10 for use in Immunocytochemistry.
Key Applications
  • Immunocytochemistry
Biological Information
ImmunogenPurified recombinant fragment of human MAPK10 expressed in E. Coli.
Clone10E4A4
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • MAPK10
  • JNK3
  • JNK3A
  • PRKM10
  • SAPK1B
Purification MethodUnpurified
UniProt Number
Molecular Weight53 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceImmunocytochemistry Analysis (ICC): A 1:200-1,000 dilution from a representative lot detected MAPK10 in A431 and HeLa cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN1176 04055977171976