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MABD50 Anti-MyT1L Antibody, clone 20B4.1

Detect the MyT1L protein using this Anti-MyT1L, clone 20B4.1 validated for use in WB & IHC.

Anti-MyT1L Antibody, clone 20B4.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: MYT1L UniProt Number: Q9UL68
MABD50
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABD50
DescriptionAnti-MyT1L Antibody, clone 20B4.1
Alternate Names
  • Myelin transcription factor 1-like protein
  • MyT1-L
  • MyT1L
Background InformationMyelin transcription factor 1-like (Myt1L) is a zinc finger protein belonging to the myelin transcription factor 1 family. It influences the expression of genes involved in the proliferation and differentiation of oligodentrocytes in the developing central nervous system. Myt1L may contribute to the silencing of its target genes by recruiting Sin3B that binds to and enhances the activity of HDAC. Several studies have implicated Myt1L in the pathogenesis of complex psychiatric diseases such as schizophrenia, major depressive disorder, and bipolar disorder.
References
Product Information
FormatPurified
Control
  • Mouse E17 spinal cord tissue lysate
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect the MyT1L protein using this Anti-MyT1L, clone 20B4.1 validated for use in WB & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:10-1:50 dilution from a representative lot detected MyT1L in human pons, mouse frontal cortex, and mouse hippocampus tissues.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human MyT1L.
Clone20B4.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Mouse
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • MYT1L
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~170 kDa observed. Uniprot describes three isoforms at 21, 126, and 133 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in mouse E17 spinal cord tissue lysate.

Western Blot Analysis: A 1:1.000 dilution of this antibody detected MyT1L on 10 µg of mouse E17 spinal cord tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABD50 04053252648199

Documentation

Anti-MyT1L Antibody, clone 20B4.1 SDS

Title

Safety Data Sheet (SDS) 

Anti-MyT1L Antibody, clone 20B4.1 Certificates of Analysis

TitleLot Number
Anti-MyT1L, clone 20B4.1 - 2424835 2424835
Anti-MyT1L, clone 20B4.1 - 2090955 2090955
Anti-MyT1L, clone 20B4.1 - 2161191 2161191
Anti-MyT1L, clone 20B4.1 - 2514232 2514232
Anti-MyT1L, clone 20B4.1 - 3229390 3229390
Anti-MyT1L, clone 20B4.1 - 3487597 3487597
Anti-MyT1L, clone 20B4.1 - Q2021130 Q2021130
Anti-MyT1L, clone 20B4.1 Monoclonal Antibody 2943590
Anti-MyT1L, clone 20B4.1 Monoclonal Antibody 2920707
Anti-MyT1L, clone 20B4.1 Monoclonal Antibody 2866727