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ABE431 Anti-PTBP2 Antibody

Anti-PTBP2 Antibody is a highly specific rabbit polyclonal antibody, that targets Polypyrimidine tract-binding protein 2 & has been tested in western blotting & IP.

Anti-PTBP2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Transcription Factors Gene Symbol: PTBP2, NPTB, PTB, PTBLP UniProt Number: Q9UKA9
ABE431
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWB, IPRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABE431
DescriptionAnti-PTBP2 Antibody
Alternate Names
  • Polypyrimidine tract-binding protein 2
  • Neural polypyrimidine tract-binding protein
  • Neurally-enriched homolog of PTB
  • PTB-like protein
Background InformationPolypyrimidine tract-binding protein 2 (PTBP2) is also known as Neural polypyrimidine tract-binding protein, Neurally-enriched homolog of PTB and PTB-like protein. PTBP2 is a RNA-binding protein which targets intronic polypyrimidines and negatively regulates pre-mRNA, exonic splicing. PTBP2 also has a role in translational regulation. PTBP2 is mainly expressed in brain, but is also found in heart and skeletal muscle. Isoforms 1 and 2 are specifically expressed in neuronal tissues.
References
Product Information
FormatAffinity Purified
Control
  • Human cortex tissue lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-PTBP2 Antibody is a highly specific rabbit polyclonal antibody, that targets Polypyrimidine tract-binding protein 2 & has been tested in western blotting & IP.
Key Applications
  • Western Blotting
  • Immunoprecipitation
Application NotesWestern Blotting Analysis: 0.5 µg/mL from a representative lot detected PTBP2 in 10 µg of rat brain cortex tissue lysate.
Immunoprecipitation Analysis: 10ug from a representative lot immunoprecipitated PTBP2 in 500 µg of P19 cell lysate.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the N-terminus of human PTBP2.
EpitopeN-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the N-terminus of PTBP2.
Species Reactivity
  • Human
  • Mouse
  • Rat
Species Reactivity NoteDemonstrated to react with Human, Mouse, and Rat. Predicted to react with Bovine, Canine, Rhesus Macaque, and Gorilla based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • PTBP2
  • NPTB
  • PTB
  • PTBLP
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~57 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected PTBP2 in 10 µg of human cortex tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABE431 04053252914027