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MABN293 Anti-Peripherin-2 Antibody, clone 6B10.1

MABN293
100 µL  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, H, RWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN293
DescriptionAnti-Peripherin-2 Antibody, clone 6B10.1
Alternate Names
  • Peripherin-2
  • Retinal degeneration slow protein
  • Tetraspanin-22
  • Tspan-22
Background InformationPeripherin-2 (PRPH2) is also called Retinal degeneration slow protein (RDS) and Tetraspanin-22 (Tspan-22). Peripherin-2 is a critical factor in ocular disk morphogenesis and possibly functions as an adhesion molecule helping to stabilize and compact outer segment disks, to help maintain curvature of the rim. Peripherin-2 is expressed in the photoreceptors of the retina and in the rim of rod outer segment (ROS) disks. Peripherin-2 defects are found in different retinal diseases including cone-rod dystrophy, retinitis pigmentosa, and macular degeneration.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Peripherin-2 Antibody, clone 6B10.1 is a highly specific mouse monoclonal antibody, that targets Peripherin & has been tested in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blotting Analysis: A 1:1,000 dilution from a representative lot detected Peripherin-2 in 10 µg of human retina tissue lysate.
Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Peripherin-2 in human retina tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to the cytoplasmic domain of human Peripherin-2.
EpitopeCytoplasmic domain
Clone6B10.1
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Mouse
  • Human
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • PRPH2
  • PRPH
  • RDS
  • TSPAN22
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~35 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse eye tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Peripherin-2 in 10 µg of mouse eye tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN293 04053252923715

Documentation

Anti-Peripherin-2 Antibody, clone 6B10.1 SDS

Title

Safety Data Sheet (SDS) 

Anti-Peripherin-2 Antibody, clone 6B10.1 Certificates of Analysis

TitleLot Number
Anti-Peripherin-2, clone 6B10.1 - 3490858 3490858
Anti-Peripherin-2, clone 6B10.1 - 3613006 3613006
Anti-Peripherin-2, clone 6B10.1 - 3929936 3929936
Anti-Peripherin-2, clone 6B10.1 - 4035505 4035505
Anti-Peripherin-2, clone 6B10.1 - 4110906 4110906
Anti-Peripherin-2, clone 6B10.1 - 4188108 4188108
Anti-Peripherin-2, clone 6B10.1 - Q2273101 Q2273101
Anti-Peripherin-2, clone 6B10.1 -2742786 2742786
Anti-Peripherin-2, clone 6B10.1 -2809290 2809290
Anti-Peripherin-2, clone 6B10.1 Monoclonal Antibody 2992393