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MAB10422 Anti-Plexin-A3 Antibody, clone 18A9.2

Anti-Plexin-A3 Antibody, clone 18A9.2 is a Mouse Monoclonal Antibody for detection of Plexin-A3 also known as PLEXIN-A3, Semaphorin receptor SEX or Plexin-4 & has been validated in WB & IHC.

Anti-Plexin-A3 Antibody, clone 18A9.2 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases Gene Symbol: HSSEXGENE, SEX, XAP-6, PLXN3, PLXN4, Plxn3, PLXNA3 UniProt Number: P51805
MAB10422
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, H, MWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMAB10422
DescriptionAnti-Plexin-A3 Antibody, clone 18A9.2
Alternate Names
  • plexin A3
  • PLEXIN-A3
  • plexin-A3
  • Sex chromosome X transmembrane protein of HGF receptor family 3
  • Semaphorin receptor SEX
  • plexin-4
  • Plexin-4
Background InformationPlexin-A3 is a cell surface receptor for semaphorin that controls signaling for neuronal axon regulation. Plexin-A3 is thought to play a role in Sema3F and Sema3A signaling, has been described as essential for dorsal turning of the corticospinal tract axons and may be an important contributor to development of hippocampal axonal projections. Plexin-A3 has been found expressed in newly-differentiated sympathetic neurons, but not their neural crest precursors, and together with Plexin-A4, functions cooperatively to regulate the migration of sympathetic neurons and then differentially to guide the sympathetic axons.
References
Product Information
FormatPurified
Control
  • PC-12 cell lysate
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Plexin-A3 Antibody, clone 18A9.2 is a Mouse Monoclonal Antibody for detection of Plexin-A3 also known as PLEXIN-A3, Semaphorin receptor SEX or Plexin-4 & has been validated in WB & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blot Analysis: 1 µg/mL from a previous lot detected Plexin-A3 on 10 µg of HT-29 and NIH/3T3 cell lysates.

Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Plexin-A3 in colorectal carcinoma tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human Plexin-A3.
Clone18A9.2
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Rat
  • Human
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a member of the plexin class of proteins. The encoded protein is a transmembrane protein that is exposed on the cell surface. This gene is thought to be involved in epithelial and neural tissue development. [provided by RefSeq].
Gene Symbol
  • HSSEXGENE
  • SEX
  • XAP-6
  • PLXN3
  • PLXN4
  • Plxn3
  • PLXNA3
Purification MethodProtein G
UniProt Number
UniProt SummaryFUNCTION: Putative receptor involved in the development of neural and epithelial tissues.

SUBCELLUALR LOCATION: Membrane; Single-pass type I membrane protein (Potential).

TISSUE SPECIFICTY: Predominant in neural tissue during development (By similarity); widely expressed in adult tissue.

SEQUENCE SIMILARITIES: Belongs to the plexin family.

Contains 4 IPT/TIG domains.

Contains 1 Sema domain.
Molecular Weight~220 kDa observed. The calculated molecular weight of this protein is 208 kDa; however, a higher band may be observed due to glycosolation.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in PC-12 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Plexin-A3 on 10 µg of PC-12 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MAB10422 04053252749544

Documentation

Anti-Plexin-A3 Antibody, clone 18A9.2 SDS

Title

Safety Data Sheet (SDS) 

Anti-Plexin-A3 Antibody, clone 18A9.2 Certificates of Analysis

TitleLot Number
Anti-Plexin-A3, clone 18A9.2 - 2115671 2115671
Anti-Plexin-A3, clone 18A9.2 - 2370170 2370170
Anti-Plexin-A3, clone 18A9.2 - 2381785 2381785
Anti-Plexin-A3, clone 18A9.2 - 2428363 2428363
Anti-Plexin-A3, clone 18A9.2 - 2436815 2436815
Anti-Plexin-A3, clone 18A9.2 - 3286442 3286442
Anti-Plexin-A3, clone 18A9.2 - 3906477 3906477
Anti-Plexin-A3, clone 18A9.2 - NRG1845787 NRG1845787
Anti-Plexin-A3, clone 18A9.2 -2893206 2893206
Anti-Plexin-A3, clone 18A9.2 Monoclonal Antibody 2919609