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AB9094-I Anti-Sodium Pump Subunit alpha-2 Antibody

Detect Sodium Pump Subunit alpha-2 using this Anti-Sodium Pump Subunit alpha-2 Antibody validated for use in Western Blotting, Immunohistochemistry (Paraffin) and Immunoprecipitation.

Anti-Sodium Pump Subunit alpha-2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: Atp1a2 UniProt Number: P06686
AB9094-I
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWB, IH(P), IPRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB9094-I
ReplacesAB9094
DescriptionAnti-Sodium Pump Subunit alpha-2 Antibody
Alternate Names
  • Sodium/potassium-transporting ATPase subunit alpha-2
  • Na(+)/K(+) ATPase alpha-2 subunit
  • Na(+)/K(+) ATPase alpha(+) subunit
  • Sodium pump subunit alpha-2
  • Sodium Pump Subunit alpha-2
  • Anti-Sodium Pump (Na+ pump (Na+-K+-ATPase)) α 2 Isoform
  • Sodium/potassium-transporting ATPase subunit alpha-2
  • ATP1A2
Background InformationSodium/potassium-transporting ATPase subunit alpha-2 (EC 3.6.3.9; UniProt P06686; also known as Na+/K+ -ATPase alpha 2 subunit, Na(+)/K(+) ATPase alpha(+) subunit, Sodium pump subunit alpha-2) is encoded by the Atp1a2 (also known as RATATPA2) gene (Gene ID 24212) in rat. Mammalian Na+/K+ ATPase is a heteromultimeric complex composed of alpha, beta, and gamma subunits. The alpha subunit catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ across the plasma membrane. The alpha subunit contains ten transmembrane domains with both its N- and C-termini in the cytoplasm. More than 50 mutations have been identified affecting the human ATP1A2 and ATP1A3 genes that are known to cause rapid-onset Dystonia Parkinsonism, familial hemiplegic migraine, alternating hemiplegia of childhood, and variants of familial hemiplegic migraine with neurological complications including seizures and various mood disorders.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Sodium Pump Subunit alpha-2 using this Anti-Sodium Pump Subunit alpha-2 Antibody validated for use in Western Blotting, Immunohistochemistry (Paraffin) and Immunoprecipitation.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
  • Immunoprecipitation
Application NotesImmunohistochemistry Analysis (IHC): A representative lot detected Sodium Pump Subunit alpha-2 in human (1:1,000) and rat (1:250) cerebellum tissue sections.

Immunoprecipitation Analysis (IP): 10 ug from a representative lot immunoprecipitated Sodium Pump Subunit alpha-2 in 500 µg of rat brain tissue lysate.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the second cytoplasmic domain of rat Sodium Pump Subunit alpha-2.
EpitopeSecond cytoplasmic domain
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityReacts with Sodium Pump (Na+ pump (Na+-K+-ATPase)) alpha 2 isoform. The antibody does not cross react with other Na+-K+-ATPase alpha isoforms.
Species Reactivity
  • Human
  • Mouse
  • Rat
Species Reactivity NoteHuman, Mouse, Rat. Predicted to react with Bovine, Porcine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Atp1a2
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~100 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: A 1:4,000 dilution of this antibody detected Sodium Pump Subunit alpha-2 in 10 µg of rat brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB9094-I 04055977173390

Documentation

Anti-Sodium Pump Subunit alpha-2 Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-Sodium Pump Subunit alpha-2 Antibody Certificates of Analysis

TitleLot Number
Anti-Sodium Pump Subunit alpha-2 - 3228351 3228351
Anti-Sodium Pump Subunit alpha-2 - 3280268 3280268
Anti-Sodium Pump Subunit alpha-2 - 3448549 3448549
Anti-Sodium Pump Subunit alpha-2 - 3700881 3700881
Anti-Sodium Pump Subunit alpha-2 - 3907844 3907844
Anti-Sodium Pump Subunit alpha-2 - 4166974 4166974
Anti-Sodium Pump Subunit alpha-2 - 4247790 4247790
Anti-Sodium Pump Subunit alpha-2 -2796794 2796794
Anti-Sodium Pump Subunit alpha-2 -2855648 2855648
Anti-Sodium Pump Subunit alpha-2 -Q2574768 Q2574768
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Technical Info

Title
Characterization of Estrogen Receptor α Phosphorylation Sites in Breast Cancer Tissue Using the SNAP i.d® 2.0 System
White Paper: Further considerations of antibody validation and usage.