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ABC139 Anti-TSPO Antibody

ABC139
100 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC139
ReplacesMABC650
DescriptionAnti-TSPO Antibody
Alternate Names
  • Translocator protein
  • Mitochondrial benzodiazepine receptor
  • PKBS
  • Peripheral-type benzodiazepine receptor
  • PBR
Background InformationTranslocator protein (TSPO) is also called Mitochondrial benzodiazepine receptor, PKBS, or Peripheral-type benzodiazepine receptor (PBR). TSPO generates peripheral-type benzodiazepine recognition sites. TSPO has a role in cholesterol transport across mitochondrial membranes in steroidogenic cells, and may also be involved in in the transport of porphyrins and heme. TSPO is found in many tissue types, but is normally found expressed at the highest levels in steroid synthesizing tissues.
References
Product Information
FormatAffinity Purified
Control
  • Human testis tissue lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-TSPO Antibody is a rabbit polyclonal antibody, validated for use in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blotting Analysis: 1.0 µg/mL from a representative lot detected TSPO in 10 µg of HeLa cell lysate.
Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected TSPO in human thalamus, human cardiac myocytes and human cerebellum tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human TSPO.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the C-terminus of TSPO.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • TSPO
  • BZRP
  • MBR
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~16 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human testis tissue lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected TSPO in 10 µg of human testis tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABC139 04053252915970