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218775 Castanospermine, Castanospermum australe - CAS 79831-76-8 - Calbiochem

218775
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
79831-76-8C₈H₁₅NO₄

Products

Catalogue NumberPackaging Qty/Pack
218775-1MGCN Plastic ampoule 1 mg
Description
OverviewPlant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins. Resulting oligosaccharides are primarily Glu3Man7-9(GlcNAc)2. Reduces bFGF induced angiogenesis in mice. Inhibits endothelial cell migration and invasion of basement membrane. Exhibits anti-viral properties. Typically used at 1-10 µg/ml.
Catalogue Number218775
Brand Family Calbiochem®
Synonyms(1S,6S,7R,8aR)-Tetrahydroxyoctahydroindolizine
References
ReferencesAhmed, S.P., et al. 1995. Biochem. Biophys. Res. Commun. 208, 267.
Pili, R., et al. 1995. Cancer Res. 55, 2920.
Walker, B.D., et al. 1987. Proc. Natl. Acad. Sci. USA 84, 8120.
Pan, Y.T., et al. 1983. Biochemistry 22, 3975.
Saul, R., et al. 1983. Arch. Biochem. Biophys. 221, 593.
Product Information
CAS number79831-76-8
ATP CompetitiveN
FormWhite solid
Hill FormulaC₈H₁₅NO₄
Chemical formulaC₈H₁₅NO₄
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetβ-glucosidases
Purity≥98% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
218775-1MGCN 04055977218732

Documentation

Castanospermine, Castanospermum australe - CAS 79831-76-8 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Castanospermine, Castanospermum australe - CAS 79831-76-8 - Calbiochem Certificates of Analysis

TitleLot Number
218775

References

Reference overview
Ahmed, S.P., et al. 1995. Biochem. Biophys. Res. Commun. 208, 267.
Pili, R., et al. 1995. Cancer Res. 55, 2920.
Walker, B.D., et al. 1987. Proc. Natl. Acad. Sci. USA 84, 8120.
Pan, Y.T., et al. 1983. Biochemistry 22, 3975.
Saul, R., et al. 1983. Arch. Biochem. Biophys. 221, 593.

Citations

Title
  • Jenny J.L. Ho, et al. (2003) N-glycosylation is required for the surface localization of MUC17 mucin. 23, 585-592.
  • Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision31-August-2010 JSW
    Synonyms(1S,6S,7R,8aR)-Tetrahydroxyoctahydroindolizine
    DescriptionPlant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins. Resulting oligosaccharides are primarily Glu3Man7-9 (GlcNAc)2. Inhibits endothelial cell angiogenesis and tumor growth. Exhibits anti-viral properties. Typically used at 1-10 µg/ml.
    FormWhite solid
    Intert gas (Yes/No) Packaged under inert gas
    CAS number79831-76-8
    Chemical formulaC₈H₁₅NO₄
    Structure formulaStructure formula
    Purity≥98% by TLC
    SolubilityH₂O (1 mg/ml)
    Storage +2°C to +8°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    Toxicity Harmful
    Merck USA index14, 1896
    ReferencesAhmed, S.P., et al. 1995. Biochem. Biophys. Res. Commun. 208, 267.
    Pili, R., et al. 1995. Cancer Res. 55, 2920.
    Walker, B.D., et al. 1987. Proc. Natl. Acad. Sci. USA 84, 8120.
    Pan, Y.T., et al. 1983. Biochemistry 22, 3975.
    Saul, R., et al. 1983. Arch. Biochem. Biophys. 221, 593.
    Citation
  • Jenny J.L. Ho, et al. (2003) N-glycosylation is required for the surface localization of MUC17 mucin. 23, 585-592.