324896 Sigma-AldricheIF-2α Inhibitor II, Sal003 - CAS 301359-91-1 - Calbiochem
The eIF-2α Inhibitor II, Sal003, also referenced under CAS 301359-91-1, controls the biological activity of eIF-2α. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
More>> The eIF-2α Inhibitor II, Sal003, also referenced under CAS 301359-91-1, controls the biological activity of eIF-2α. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 3-Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide, Sal003
Recommended Products
Overview
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Key Spec Table
| CAS # | Empirical Formula |
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| 301359-91-1 | C₁₈H₁₅Cl₄N₃OS |
Products
| Catalogue Number | Packaging | Qty/Pack | |
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| 324896-5MGCN | Plastic ampoule | 5 mg |
| Description | |
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| Overview | A cell-permeable Salubrinal (Cat. No. 324895) analog that is reported to be more potent and soluble than Salubrinal. In addition to being a useful tool in studying elF2α-mediated cellular processes in cultures in vitro, enhanced elF2α phosphorylation by Sal003 treatment in the brain (40 pmol per animal) is shown to impair long-term memory in mice in vivo. |
| Catalogue Number | 324896 |
| Brand Family | Calbiochem® |
| Synonyms | 3-Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide, Sal003 |
| Product Information | |
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| CAS number | 301359-91-1 |
| Form | Off-white solid |
| Hill Formula | C₁₈H₁₅Cl₄N₃OS |
| Chemical formula | C₁₈H₁₅Cl₄N₃OS |
| Structure formula Image | |
| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥95% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 324896-5MGCN | 04055977196238 |
Documentation
eIF-2α Inhibitor II, Sal003 - CAS 301359-91-1 - Calbiochem SDS
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eIF-2α Inhibitor II, Sal003 - CAS 301359-91-1 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 324896 |
References
| Reference overview |
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| Raven, J.F., et al. 2008. J. Biol. Chem. 283, 3097. Baltzis, D., et al. 2007. J. Biol. Chem. 282, 31675. Kazemi, S., et al. 2007. Mol. Biol. Cell 18, 3635. Costa-Mattioli, M., et al. 2007. Cell 129, 195. Robert, F., et al. 2006. Mol. Biol. Cell 17, 4632. |