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100073 15-PGDH Inhibitor - CAS 1239610-60-6 - Calbiochem

100073
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概述

Replacement Information

重要规格表

CAS #Empirical Formula
1239610-60-6C₁₉H₂₃NO₄S

Products

产品目录编号包装 数量 / 包装
100073-10MGCN 玻璃瓶 10 mg
Description
OverviewA cell-permeable, thiazolidinedione derivative that acts as a 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor (IC50 = 25 nM). It is shown to increase PGE2 levels in IL-1β-stimulated A549 cells, dose-dependently, in the range of 0–20 µM, and elicits cochlear blood flow (CBF) increase by 15% and 55% when applied intravenously to 250 g guinea pigs at 10 µg and 20 µg respectively.
Catalogue Number100073
Brand Family Calbiochem®
Synonyms5-(4-(2-Cyclohexylethoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione
References
ReferencesWu, Y., et al. 2011. J. Med. Chem. 54, 5260.
Product Information
CAS number1239610-60-6
FormYellow solid
Hill FormulaC₁₉H₂₃NO₄S
Chemical formulaC₁₉H₂₃NO₄S
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
100073-10MGCN 04055977226195

Documentation

15-PGDH Inhibitor - CAS 1239610-60-6 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

15-PGDH Inhibitor - CAS 1239610-60-6 - Calbiochem 分析证书

标题批号
100073

参考

参考信息概述
Wu, Y., et al. 2011. J. Med. Chem. 54, 5260.
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision08-June-2012 JSW
Synonyms5-(4-(2-Cyclohexylethoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione
DescriptionA cell-permeable, thiazolidinedione derivative that acts as a 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor (IC50 = 25 nM). It is shown to increase PGE2 levels in IL-1β-stimulated A549 cells, dose-dependently, in the range of 0–20 µM, and elicits cochlear blood flow (CBF) increase by 15% and 55% when applied intravenously to 250 g guinea pigs at 10 µg and 20 µg respectively.
FormYellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number1239610-60-6
Chemical formulaC₁₉H₂₃NO₄S
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO (100 mg/ml; clear, pale yellow solution)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesWu, Y., et al. 2011. J. Med. Chem. 54, 5260.