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116860 Adenosine Deaminase Inhibitor, DCF - CAS 53910-25-1 - Calbiochem

The Adenosine Deaminase Inhibitor, DCF, also referenced under CAS 53910-25-1, controls the biological activity of Adenosine Deaminase.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

同义词: 2ʹ-Deoxycoformycin, (8R)-3-(2-deoxy-β-D-erythro- pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, Pentostatin, S. antibioticus

116860
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概述

Replacement Information

重要规格表

CAS #Empirical Formula
53910-25-1C₁₁H₁₆N₄O₄

Products

产品目录编号包装 数量 / 包装
116860-10MGCN 玻璃瓶 10 mg
Description
OverviewA cell-permeable purine nucleoside compound that acts as a highly potent, tight binding transition state analog inhibitor of adenosine deaminase (ADA; Ki= 2.5 pM against partially purified human erythrocytes, and 0.48 to 9.1 nM against rat liver, rat intestine, rat hepatoma and human B cells). Reported to be an immunomodulator and exert selective toxicity towards lymphocytes.
Catalogue Number116860
Brand Family Calbiochem®
Synonyms2ʹ-Deoxycoformycin, (8R)-3-(2-deoxy-β-D-erythro- pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, Pentostatin, S. antibioticus
References
ReferencesRobak, T. 2007. Cancer Treat. Rev. 33, 710.
Klohs, W.D. and Kraker, A.J., 1992. Pharmacol. Rev. 44, 459.
Agarwal, R.P., et al. 1977. Biochem. Pharmacol. 26, 359.
Product Information
CAS number53910-25-1
FormWhite solid
Hill FormulaC₁₁H₁₆N₄O₄
Chemical formulaC₁₁H₁₆N₄O₄
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 62-63

Possible risk of impaired fertility.
Possible risk of harm to the unborn child.
S PhraseS: 36/37/39-45

Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Harmful & Carcinogenic / Teratogenic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
116860-10MGCN 04055977223934

Documentation

Adenosine Deaminase Inhibitor, DCF - CAS 53910-25-1 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

Adenosine Deaminase Inhibitor, DCF - CAS 53910-25-1 - Calbiochem 分析证书

标题批号
116860

参考

参考信息概述
Robak, T. 2007. Cancer Treat. Rev. 33, 710.
Klohs, W.D. and Kraker, A.J., 1992. Pharmacol. Rev. 44, 459.
Agarwal, R.P., et al. 1977. Biochem. Pharmacol. 26, 359.
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-May-2012 JSW
Synonyms2ʹ-Deoxycoformycin, (8R)-3-(2-deoxy-β-D-erythro- pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, Pentostatin, S. antibioticus
DescriptionA cell-permeable purine nucleoside compound that acts as a highly potent, tight binding transition state analog inhibitor of adenosine deaminase (ADA; Ki= 2.5 pM against partially purified human erythrocytes, and 0.48 to 9.1 nM against rat liver, rat intestine, rat hepatoma and human B cells). Reported to be an immunomodulator and exert selective toxicity towards lymphocytes.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number53910-25-1
Chemical formulaC₁₁H₁₆N₄O₄
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (10 mg/ml; clear, colorless solution) or H₂O (50 mg/ml; clear, colorless solution)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Harmful & Carcinogenic / Teratogenic
ReferencesRobak, T. 2007. Cancer Treat. Rev. 33, 710.
Klohs, W.D. and Kraker, A.J., 1992. Pharmacol. Rev. 44, 459.
Agarwal, R.P., et al. 1977. Biochem. Pharmacol. 26, 359.