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ABS434 Anti-ApoA4 Antibody

ABS434
100 µg  
Purchase on Sigma-Aldrich

特卖

概述

Replacement Information

重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABS434
DescriptionAnti-ApoA4 Antibody
Alternate Names
  • Apolipoprotein A4
  • Apolipoprotein A-IV
  • ApoA-IV
  • APO-AIV
  • ApoA4
Background InformationApoA4, also known as Apolipoprotein A4 or ApoA-IV, is a member of the apolipoprotein A1/A4/E family. ApoA4 is a major component of HDL and it can be found on the surface of newly synthesized chylomicrons. Studies have shown that APoA4 is required for efficient activation of lipoprotein lipase by ApoC-II, which is a potent activator of Lecithin Cholesterol Acyltransferase (LCAT). Other evidence points out that ApoA4 may have a role in chylomicrons and VLDL secretion and catabolism. The physiological function of ApoA4 is not confirmed yet, but evidence from several in vitro studies indicate that it may play a role in the reverse cholesterol transport pathway, transporting cholesterol from peripheral cells back to the liver. ApoA4 is synthesized primarily in the intestine and secreted in the plasma.
References
Product Information
FormatAffinity Purified
Control
  • Human liver tissue lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-ApoA4 Antibody is a highly specific rabbit polyclonal antibody, that targets Apolipoprotein A & has been tested in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected ApoA4 in human colon tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human ApoA4.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • APOA4
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~38 kDa observed. Uncharacterized bands may appear in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected ApoA4 in 15 µg of human liver tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABS434 04053252923517