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ABN255 Anti-Bassoon Antibody

ABN255
100 µL  
Purchase on Sigma-Aldrich

特卖

概述

Replacement Information

重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, H, RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN255
DescriptionAnti-Bassoon Antibody
Alternate Names
  • Bassoon
  • Protein bassoon
Background InformationProtein bassoon (also known as bassoon presynaptic cytomatrix protein, neuronal double zinc finger protein, zinc finger protein 231) is a cytoplasmic protein encoded by the BSN gene in human (also known as KIAA0434 and ZNF23118). Bassoon is found primarily in neurons in brain (PMID 9806829) and most likely functions as a scaffolding protein involved in organizing the presynaptic cytoskeleton. Murine and rodent orthologs are reported to be detected in axon terminals of hippocampal neurons, where it is highly concentrated in the vicinity of the active zone, indicating a potential involvement in cytomatrix organization at the site of neurotransmitter release (PMID 9679147).
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-Bassoon Antibody is an antibody against Bassoon for use in Western Blotting and Immunohistochemistry (Paraffin).
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Bassoon in rat cerebellum, human cerebral cortex, rat colon, mouse small intestine, and rat kidney tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to mouse Bassoon.
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityThis antibody is predicted to cross react with both isoforms.
Species Reactivity
  • Mouse
  • Human
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Bsn
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~420 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: A 1:5,000 dilution of this antibody detected Bassoon in 10 µg of mouse brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABN255 04055977158953