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ABT338 Anti-EBI3 Antibody

Detect IL-27 using this rabbit polyclonal antibody, Anti-EBI3 Antibody validated for use in western blotting, IHC & Immunofluorescence.

Anti-EBI3 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Cytokines & Cytokine Receptors Gene Symbol: EBI3, IL27B UniProt Number: Q14213
ABT338
100 µg  
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概述

Replacement Information

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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT338
DescriptionAnti-EBI3 Antibody
Alternate Names
  • Interleukin-27 subunit beta
  • IL-27 subunit beta
  • IL-27B
  • Epstein-Barr virus-induced gene 3 protein
  • EBV-induced gene 3 protein
Background InformationEpstein-Barr virus-induced gene 3 protein (EBI3), also known as Interleukin-27 subunit beta (IL27B), is a member of the type I cytokine receptor family (Type 3 subfamily) that is composed of two subunits: interleukin-27 (IL-27) and IL-35. EBI3 regulates T-helper cell development, stimulates cytotoxic T-cell activity, suppresses T-cell proliferation, and induces isotype switching in B-cells. EBI3 also plays an important role in its antitumor activity as well as its antiangiogenic activity.
References
Product Information
FormatAffinity Purified
Control
  • K562 cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect IL-27 using this rabbit polyclonal antibody, Anti-EBI3 Antibody validated for use in western blotting, IHC & Immunofluorescence.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Immunofluorescence
Application NotesImmunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected EBI3 in human spleen tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected EBI3 in human spleen cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human EBI3.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the C-terminus of EBI3.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • EBI3
  • IL27B
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~37 kDa observed. Uncharacterized bands may appear in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting/Peptide Inhibition Assay in K562 cell lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected EBI3 in 15 µg of K562 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABT338 04053252905506