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MABS460 Sigma-AldrichAnti-FGF23 Antibody, clone 278-2

Anti-FGF23 Antibody, clone 278-2 is a mouse monoclonal antibody & validated for use in western blotting.

Anti-FGF23 Antibody, clone 278-2 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: FGF23, HYPF UniProt Number: Q9GZV9

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB, FC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABS460
Description	Anti-FGF23 Antibody, clone 278-2
Alternate Names	Fibroblast growth factor 23 FGF-23 Phosphatonin Tumor-derived hypophosphatemia-inducing factor Fibroblast growth factor 23 N-terminal peptide Fibroblast growth factor 23 C-terminal peptide
Background Information	Fibroblast growth factor 23 (FGF-23) is also called Phosphatonin and Tumor-derived hypophosphatemia-inducing factor. FGF-23 belongs to the heparin-binding growth factors family and has several important functions including: regulation of phosphate homeostasis, inhibition of renal tubular phosphate transport, upregulation of EGR1 expression, regulation of vitamin-D metabolism, and negative regulation of osteoblast differentiation and matrix mineralization. FGF-23 is expressed in osteogenic cells, adult trabecular bone, osteocytes and flattened bone-lining cells (inactive osteoblasts). Defects in FGF23 can lead to autosomal dominant hypophosphataemic rickets (ADHR) and hyperphosphatemic familial tumoral calcinosis (HFTC).

References

Product Information
Format	Purified
Control	Human salivary gland tissue lysate
Presentation	Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-FGF23 Antibody, clone 278-2 is a mouse monoclonal antibody & validated for use in western blotting.
Key Applications	Western Blotting Flow Cytometry
Application Notes	Flow Cytometry Analysis: 2 µg from a representative lot detected FGF23 in Jurkat and human PMBC cells.

Biological Information
Immunogen	Corresponding to human FGF23.
Clone	278-2
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Isotype	IgG1κ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_065689
Gene Symbol	FGF23 HYPF
Purification Method	Protein A Purfied
UniProt Number	Q9GZV9
Molecular Weight	~25 kDa observed

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in human salivary gland tissue lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected FGF23 in 10 µg of human salivary gland tissue lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABS460	04053252921902

Documentation

Anti-FGF23 Antibody, clone 278-2 MSDS

职位
物料安全数据表 (MSDS)

Anti-FGF23 Antibody, clone 278-2 分析证书

标题	批号
Anti-FGF23, clone 278-2 - 3242718	3242718
Anti-FGF23, clone 278-2 - 3385855	3385855
Anti-FGF23, clone 278-2 - 3600709	3600709
Anti-FGF23, clone 278-2 - Q2257010	Q2257010
Anti-FGF23, clone 278-2 -2647563	2647563
Anti-FGF23, clone 278-2 -2679506	2679506
Anti-FGF23, clone 278-2 -2745862	2745862
Anti-FGF23, clone 278-2 Monoclonal Antibody	3058493
Anti-FGF23, clone 278-2 Monoclonal Antibody	3091969

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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