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ABS764 Anti-GPAT-1 Antibody

Anti-GPAT-1 Antibody is an antibody against GPAT-1 for use in western blotting, IHC & immunofluorescence.

Anti-GPAT-1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: GPAM, GPAT1 UniProt Number: Q9HCL2
ABS764
100 µg  
Purchase on Sigma-Aldrich

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概述

Replacement Information

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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABS764
ReplacesMABS402
DescriptionAnti-GPAT-1 Antibody
Alternate Names
  • Glycerol-3-phosphate acyltransferase 1, mitochondrial
  • GPAT-1
Background InformationGlycerol-3-phosphate acyltransferase 1, mitochondrial (GPAT-1) is located on the mitochondrial outer membrane, allowing reciprocal regulation with carnitine palmitoyltransferase-1. It is thought to be critical for the development of hepatic steatosis; steatosis triggered by GPAT-1 overexpression leads to hepatic and possibly peripheral insulin resistance. GPAT-1 is transcriptionally upregulated by insulin and sterol regulatory element binding protein (SREBP-1) and downregulated by AMP-activated protein kinase. Mice deficient in GPAT-1 exhibit decreased triacylglycerol (TAG) in cardiomyocytes even in high-fat diets, suggesting that GPAT-1 contributes significantly to TAG accumulation in heart tissue during lipogenic or high fat diets.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-GPAT-1 Antibody is an antibody against GPAT-1 for use in western blotting, IHC & immunofluorescence.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Immunofluorescence
Application NotesImmunohistochemistry Analysis: 2.5 μg/mL from a representative lot detected GPAT-1 in rat brain tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected GPAT-1 in rat brain cells.
Biological Information
ImmunogenKLH-conjugated synthetic peptide corresponding to the C-terminus of human GPAT-1.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Gene Symbol
  • GPAM
  • GPAT1
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~82 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: 2 μg/mL of this antibody detected GPAT-1 in rat brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABS764 04053252944062