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ABF221 Anti-IRAK-2 Antibody

Anti-IRAK-2 Antibody is a highly specific rabbit polyclonal antibody, that targets IRAK2 & has been tested in western blotting, ICC & Immunofluorescence.

Anti-IRAK-2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunological Signaling Gene Symbol: IRAK2 UniProt Number: O43187
ABF221
100 µg  
Purchase on Sigma-Aldrich

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概述

Replacement Information

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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, ICC, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABF221
DescriptionAnti-IRAK-2 Antibody
Alternate Names
  • Interleukin-1 receptor-associated kinase-like 2
  • IRAK-2
Background InformationInterleukin-1 receptor-associated kinase-like 2 (IRAK-2) binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. IRAK-2 also mediates activation of NF-κB, which is a pivotal transcription factor mediating inflammatory and immune response. Additionally, IRAK-2 may play an important role in IL-1R and TLR mediated inflammatory response. IRAK-2 is expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.
References
Product Information
FormatAffinity Purified
Control
  • HeLa and K562 cell lysates
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-IRAK-2 Antibody is a highly specific rabbit polyclonal antibody, that targets IRAK2 & has been tested in western blotting, ICC & Immunofluorescence.
Key Applications
  • Western Blotting
  • Immunocytochemistry
  • Immunofluorescence
Application NotesImmunocytochemistry Analysis: 2 µg/mL from a representative lot detected IRAK-2 in HeLa cells.

Immunofluorescence Analysis: 10 µg/mL from a representative lot detected IRAK-2 in HeLa cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human IRAK-2.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • IRAK2
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~65 kDa observed. Uncharacterized bands may appear in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in HeLa and K562 cell lysates.

Western Blot Analysis: 2 µg/mL of this antibody detected IRAK-2 in 15 µg of HeLa and K562 cell lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABF221 04053252910128