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ABE91 Anti-JMJD8 Antibody

Anti-JMJD8 Antibody is a Rabbit Polyclonal Antibody for detection of JMJD8 also known as Jumonji domain-containing protein 8 & has been validated in WB.

Anti-JMJD8 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Histone Modifying Proteins Gene Symbol: JMJD8, C16orf20, PP14397 UniProt Number: Q96S16
ABE91
100 µg  
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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, Po, Chp, Rhesus Macaque, Ca, EqWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABE91
DescriptionAnti-JMJD8 Antibody
Alternate Names
  • JMJD
  • JmjC domain-containing protein 8
  • Jumonji domain-containing protein 8
Background InformationCovalent modification of histones plays critical role in regulating chromatin structure and transcription. JMJD8 is one member of the family of JmjC domain-containing histone demethylation (JHDM) enzymes. These proteins remove specific methyl marks from histones. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed. While two isoforms of JMJD8 have been described, further study is still required to clarify the roles and mechanisms of JMJD8 among other JHDM protein family members.
References
Product Information
FormatAffinity Purified
Control
  • HeLa nuclear extract
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-JMJD8 Antibody is a Rabbit Polyclonal Antibody for detection of JMJD8 also known as Jumonji domain-containing protein 8 & has been validated in WB.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human JMJD8.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
  • Pig
  • Chimpanzee
  • Rhesus Macaque
  • Canine
  • Horse
Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Porcine, Chimpanzee, Rhesus Macaque, Canine, and Equine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • JMJD8
  • C16orf20
  • PP14397
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~37 kDa observed. Two isoforms with molecular weights of ~34 kDa and ~37 kDa have been described. An uncharacterized band at ~160 kDa may be observed in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in HeLa nuclear extract.

Western Blot Analysis: 1 mg/mL of this antibody dected JMJD8 in 10 mg of HeLa nuclear extract.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABE91 04053252754975