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528215 Anti-PAI-1 Mouse mAb (MA-33B8)

This Anti-PAI-1 Mouse mAb (MA-33B8) is validated for use in Immunoblotting, Neutralization Studies for the detection of PAI-1.

Anti-PAI-1 Mouse mAb (MA-33B8) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

同义词: Anti-Plasminogen Activator Inihibitor-1

528215
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概述

Replacement Information

重要规格表

Species ReactivityHostAntibody Type
H, RbMMonoclonal Antibody

Products

产品目录编号包装 数量 / 包装
528215-100UGCN 塑胶安瓿;塑胶针药瓶 100 μg
Description
OverviewRecognizes the ~50 kDa PAI-1 protein.
Catalogue Number528215
Brand Family Calbiochem®
SynonymsAnti-Plasminogen Activator Inihibitor-1
References
ReferencesMontes, R., et al. 2000. Thromb. Haemost. 84, 65.
Verhamme, I., et al. 1999. J. Biol. Chem. 274, 17511.
Debrock, S., and Declerck, P.J. 1997. Biochim. Biophys. Acta 1337, 257.
Product Information
FormLiquid
FormulationIn 100 mM NaCl, 50 mM sodium phosphate buffer, pH 7.4.
PreservativeNone
Quality LevelMQ100
Applications
Application ReferencesNeutralization Studies Verhamme, I., et al. 1999. J. Biol. Chem. 274, 17511.
Key Applications Immunoblotting (Western Blotting)
Neutralization Studies
Application NotesImmunoblotting (10 µg/ml)
Neutralization Studies (see application references)
Application CommentsRapidly inactivates PAI-1 (Plasminogen Activator Inhibitor-1) to the latent form. Like the native latent form, PAI-1 inactivated by antibody was protected from cleavage by elastase. Also shown to reduce renal fibrin deposits in a rabbit model of endotoxemia. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
Immunogenhuman tPA-PAI-1 complex
ImmunogenHuman
CloneMA-33B8
HostMouse
Purity≥ 90% by SDS-PAGE
IsotypeIgG
Species Reactivity
  • Human
  • Rabbit
Antibody TypeMonoclonal Antibody
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
528215-100UGCN 04055977196511

Documentation

Anti-PAI-1 Mouse mAb (MA-33B8) MSDS

职位

物料安全数据表 (MSDS) 

Anti-PAI-1 Mouse mAb (MA-33B8) 分析证书

标题批号
528215

参考

参考信息概述
Montes, R., et al. 2000. Thromb. Haemost. 84, 65.
Verhamme, I., et al. 1999. J. Biol. Chem. 274, 17511.
Debrock, S., and Declerck, P.J. 1997. Biochim. Biophys. Acta 1337, 257.
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-March-2009 JSW
SynonymsAnti-Plasminogen Activator Inihibitor-1
ApplicationImmunoblotting (10 µg/ml)
Neutralization Studies (see application references)
DescriptionPurified mouse monoclonal antibody. Recognizes the ~50 kDa PAI-1 protein.
HostMouse
Immunogen speciesHuman
Immunogenhuman tPA-PAI-1 complex
CloneMA-33B8
IsotypeIgG
Specieshuman, rabbit
FormLiquid
FormulationIn 100 mM NaCl, 50 mM sodium phosphate buffer, pH 7.4.
Concentration Label Please refer to vial label for lot-specific concentration
Purity≥ 90% by SDS-PAGE
PreservativeNone
CommentsRapidly inactivates PAI-1 (Plasminogen Activator Inhibitor-1) to the latent form. Like the native latent form, PAI-1 inactivated by antibody was protected from cleavage by elastase. Also shown to reduce renal fibrin deposits in a rabbit model of endotoxemia. Variables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesMontes, R., et al. 2000. Thromb. Haemost. 84, 65.
Verhamme, I., et al. 1999. J. Biol. Chem. 274, 17511.
Debrock, S., and Declerck, P.J. 1997. Biochim. Biophys. Acta 1337, 257.
Application referencesNeutralization Studies Verhamme, I., et al. 1999. J. Biol. Chem. 274, 17511.