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ABN1372 Anti-Potassium Channel KCNQ5 Antibody

ABN1372
50 µg  
Purchase on Sigma-Aldrich

特卖

概述

Replacement Information

重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RIHC, WBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN1372
ReplacesAB5599
DescriptionAnti-Potassium Channel KCNQ5 Antibody
Alternate Names
  • Potassium voltage-gated channel subfamily KQT member 5
  • Potassium channel subunit alpha KvLQT5
  • KQT-like 5
  • Voltage-gated potassium channel subunit Kv7.5
  • KCNQ5
Background InformationKCNQ5 is subunit one of a voltage gated potassium channel expressed in the brain and other tissues. KCNQ5 forms the complete channel with KCNQ3. This channel gives rise to the "M" potassium current which is a slowly activating and deactivating current. This current plays a critical role in determining the subthreshold electrical excitability of neurons. KCNQ5 is strongly expressed in the brain but also in skeletal muscle and vascular smooth muscle cells. KCNQ5 activity is also regulated via phosphorylation by PKC and that kinase regulation may be a key to regulating excitability in neurons and muscle cells.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit Polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Potassium Channel KCNQ5 Antibody is validated for use in Immunohistochemistry and Western Blotting for the detection of Potassium Channel KCNQ5.
Key Applications
  • Immunohistochemistry
  • Western Blotting
Application NotesWestern Blotting Analysis: A 0.1µg/mL dilution from a representative lot detected Potassium Channel KCNQ5 in 10 µg of transient over-expression of Potassium Channel KCNQ5 in HEK293 cell lysate.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the Human Potassium Channel KCNQ5.
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityWestern Blotting Analysis was tested on overxpressing transfected cell lysate.
Species Reactivity
  • Human
  • Rat
Species Reactivity NoteHuman, Rat. Predicted to react with Canine, Feline, Rhesus Macaque, Giant Panda, Chimpanzee based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~103 kDa observed. Predicted to cross react to Isoforms 1, 2, and 3. Additional bands are detected in endogenous lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunohistochemistry in human cerebral cortex tissue.

Imunnohistochemistry Analysis: A 1:2,000 dilution of this antibody detected Potassium Channel KCNQ5 in human cerebral cortex tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size50 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABN1372 04055977112610

Documentation

Anti-Potassium Channel KCNQ5 Antibody MSDS

职位

物料安全数据表 (MSDS) 

Anti-Potassium Channel KCNQ5 Antibody 分析证书

标题批号
Anti-Potassium Channel KCNQ5 Q2476155
Anti-Potassium Channel KCNQ5 - 3093511 3093511
Anti-Potassium Channel KCNQ5 - 3272275 3272275
Anti-Potassium Channel KCNQ5 - 3385871 3385871
Anti-Potassium Channel KCNQ5 - 3689950 3689950
Anti-Potassium Channel KCNQ5 - 3904326 3904326
Anti-Potassium Channel KCNQ5 - 4116917 4116917
Anti-Potassium Channel KCNQ5 - 4284132 4284132