数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

MABC615 Sigma-AldrichAnti-TNFα Receptor Antibody, clone 13F9.1

Anti-TNF apha Receptor Antibody, clone 13F9.1 is a highly specific mouse monoclonal antibody, that targets TNFα Receptor & has been tested in Western Blotting, and Immunohistochemistry.

Anti-TNFα Receptor Antibody, clone 13F9.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
技术信息

Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: TNFRSF1A, TNFAR, TNFR1 UniProt Number: P19438

Recommended Products

概述

Replacement Information

特卖

100% Performance Guaranteed

重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M	WB, IHC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABC615
Description	Anti-TNFα Receptor Antibody, clone 13F9.1
Alternate Names	Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor 1 TNF-R1 Tumor necrosis factor receptor type I TNF-RI TNFR-I p55 p60 CD120a Tumor necrosis factor receptor superfamily member 1A, membrane form Tumor necrosis factor-binding protein 1 TBPI
Background Information	Tumor necrosis factor receptor superfamily member 1A (UniProt P19438; also known as CD120a, p55, p60, TNF-R1, TNF-RI, TNFR-I, Tumor necrosis factor-alpha receptor, Tumor necrosis factor receptor type 1) is encoded by the TNFRSF1A (also known as FPF, MS5, TNFAR, TNFAR55, TNFAR60, TNFR1) gene (Gene ID 7132) in human. It functions as a receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. Upon activation, TNFalpha receptor mediates apoptotic, anti-viral, and other cellular signaling events. Binding of TNF-alpha to the extracellular domain of TNF receptor leads to homotrimerization. Proteolytic cleavage results in the relese of Tumor necrosis factor-binding protein 1 (TBP1). Defects in TNF receptor cause tumor necrosis factor receptor-associated periodic syndrome (TRAPS), a hereditary periodic fever syndrome characterized by recurrent fever, abdominal pain, localized tender skin lesions and myalgia.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-TNF apha Receptor Antibody, clone 13F9.1 is a highly specific mouse monoclonal antibody, that targets TNFα Receptor & has been tested in Western Blotting, and Immunohistochemistry.
Key Applications	Western Blotting Immunohistochemistry
Application Notes	Western Blotting Analysis: 1.0 µg/mL from a representative lot detected TNFα Receptor in 10 µg of HepG2 and RAW264 cell lysate. Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected TNFα Receptor in human colon tissue and human colon cancer cells.

Biological Information
Immunogen	GST-tagged recombinant protein corresponding to the extracellular domain of human TNFα Receptor.
Epitope	Extracellular domain
Clone	13F9.1
Concentration	Please refer to lot specific datasheet.
Host	Mouse
Specificity	Expected to react with spliced isoforms 1/FL-TNFR1, 2, 4/Delta6-TNFR1, and 5, but not isoform 3.
Isotype	IgG1κ
Species Reactivity	Human Mouse
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_001056
Gene Symbol	TNFRSF1A TNFAR TNFR1
Purification Method	Protein G Purified
UniProt Number	P19438
Molecular Weight	~50/43 kDa observed. 50.5 kDa (isoform 1/FL-TNFR1 calculated), 38.7 kDa (isoform 2 calculated), 25.6 kDa (isoform 4/Delta6-TNFR1 calculated), 24.2 kDa (isoform 5 calculated).

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in Jurkat cell lysate. Western Blotting Analysis: 1.0 µg/mL of this antibody detected TNFα Receptor in 10 µg of Jurkat cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 μg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABC615	04055977171419

Documentation

Anti-TNFα Receptor Antibody, clone 13F9.1 MSDS

职位
物料安全数据表 (MSDS)

Anti-TNFα Receptor Antibody, clone 13F9.1 分析证书

标题	批号
Anti-TNFα Receptor, clone 13F9.1 - 3562044	3562044
Anti-TNFα Receptor, clone 13F9.1 - 4089937	4089937
Anti-TNFα Receptor, clone 13F9.1 -Q2573230	Q2573230

技术信息

标题
Characterization of Estrogen Receptor α Phosphorylation Sites in Breast Cancer Tissue Using the SNAP i.d® 2.0 System
White Paper: Further considerations of antibody validation and usage.

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

此产品已添加到您的购物车。