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MABC988 Anti-TRADD Antibody, clone 1G6.1

This Anti-TRADD Antibody, clone 1G6.1 is validated for use in Western Blotting, Immunohistochemistry (Paraffin) for the detection of TRADD.

Anti-TRADD Antibody, clone 1G6.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: TRADD UniProt Number: Q15628
MABC988
100 μg  
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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RWB, IH(P)MPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC988
DescriptionAnti-TRADD Antibody, clone 1G6.1
Alternate Names
  • Tumor necrosis factor receptor type 1-associated DEATH domain protein
  • TRADD
  • TNFR1-associated DEATH domain protein
  • TNFRSF1A-associated via death domain
Background InformationTumor necrosis factor receptor type 1-associated DEATH domain protein (UniProt Q15628; also known as TNFR1-associated death domain protein, TNFRSF1A-associated via death domain, Tumor necrosis factor receptor-1-associated protein) is encoded by the TRADD (also known as Hs.89862) gene (Gene ID 8717) in human. TRADD is an adapter protein that interacts with the TNFR1 receptor, and mediates the activation of programmed cell death and NF-κB activation. TRADD exhibits similar structural and functional features, as well as subcellular localization as the adaptor protein Fas-associated death domain (FADD). Both proteins contain a C-terminal death domain (DD) and function as mediators of death receptors-mediated signaling pathways.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-TRADD Antibody, clone 1G6.1 is validated for use in Western Blotting, Immunohistochemistry (Paraffin) for the detection of TRADD.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected TRADD in human small intestine, human lymphoma, rat colon, and rat spleen tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human TRADD.
Clone1G6.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityReactivity toward human TRADD spliced isoform 2 has not been determined.
IsotypeIgG1κ
Species Reactivity
  • Human
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • TRADD
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~35 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Jurkat cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected TRADD in 10 µg of Jurkat cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
MABC988 04055977298277