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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

MABC536 Sigma-AldrichAnti-Vasohibin-2, clone 5E3 Antibody

Anti-Vasohibin-2 antibody, clone 5E3 is an antibody against Vasohibin-2 for use in western blotting & IHC.

Anti-Vasohibin-2, clone 5E3 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考

Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: VASH2, VASHL UniProt Number: Q86V25

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M	WB, IHC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABC536
Description	Anti-Vasohibin-2, clone 5E3 Antibody
Alternate Names	Vasohibin-2 Vasohibin-like protein
Background Information	Vasohibin-2, also known as Vasohibin-like protein, and encoded by the gene VASH2/VASHL, is a developmental regulator protein of angiogenesis induced by VEGF and present in various embryonic organs at six to 12 twelve weeks of development in humans. Vasohibin-2 acts as an angiogenesis inhibitor and is thought to help regulate organ vessel formation and maturation. In cancer, Vascohibin-2 appears to act to promote angiogenesis and is expressed in many cancers. In cancer cells, there are two isoforms. VASH2 (with 355 amino acid residues) is located in the cytoplasm while VASH2 (with 311 amino acid residues) is located in the nucleus. The former was found to be a relatively low abundance protein.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG1κ in buffer containing PBS without preservatives .
Quality Level	MQ100

Applications
Application	Anti-Vasohibin-2 antibody, clone 5E3 is an antibody against Vasohibin-2 for use in western blotting & IHC.
Key Applications	Western Blotting Immunohistochemistry
Application Notes	Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Vasohibin 2 in human placenta tissue. Immunohistochemistry Analysis: A representative lot detected Vasohibin 2 in human and mouse embryonic lung tissue (Shibuya, T., et al. (2006). American Heart Association. 26:1051-1057).

Biological Information
Immunogen	KLH-conjugated linear peptide corresponding to human Vasohibin 2.
Clone	5E3
Concentration	1 mg/mL
Host	Mouse
Isotype	IgG1κ
Species Reactivity	Human Mouse
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_001129946
Gene Symbol	VASH2 VASHL
Purification Method	Protein G Purified
UniProt Number	Q86V25
Molecular Weight	~40 kDa observed. Uncharacterized band(s) may appear in some lysates.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in HUVEC cell lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected Vasohibin 2 in 10 µg of HUVEC cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

Storage and Shipping Information

Storage Conditions

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABC536	04053252975752

Documentation

Anti-Vasohibin-2, clone 5E3 Antibody MSDS

职位
物料安全数据表 (MSDS)

Anti-Vasohibin-2, clone 5E3 Antibody 分析证书

标题	批号
Anti-Vasohibin-2, clone 5E3	3083528
Anti-Vasohibin-2, clone 5E3 - Q2426884	Q2426884
Anti-Vasohibin-2, clone 5E3 - 3229377	3229377
Anti-Vasohibin-2, clone 5E3 - 3385863	3385863
Anti-Vasohibin-2, clone 5E3 - 3819208	3819208
Anti-Vasohibin-2, clone 5E3 - 3862697	3862697
Anti-Vasohibin-2, clone 5E3 - 4159886	4159886
Anti-Vasohibin-2, clone 5E3 -2717553	2717553
Anti-Vasohibin-2, clone 5E3 Monoclonal Antibody	2923051
Anti-Vasohibin-2, clone 5E3 Monoclonal Antibody	3559007

参考

参考概述	公共医疗ID
Isolation and characterization of vasohibin-2 as a homologue of VEGF-inducible endothelium-derived angiogenesis inhibitor vasohibin. Shibuya, Takumi, et al. Arterioscler. Thromb. Vasc. Biol., 26: 1051-7 (2006) 2006 显示摘要 We recently isolated vasohibin, a novel vascular endothelial growth factor (VEGF)-inducible endothelium-derived angiogenesis inhibitor. Our aim is to find DNA sequences homologous to vasohibin and determine their expression profile.	16528006

参考概述

公共医疗ID

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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