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SCT052 BioTracker Far-Red Peroxynitrite Live Cell Dye

Live cell imaging probe for detection and imaging peroxynitrite, a highly cytotoxic reactive nitrogen species (RNS).

SCT052
1 mg  
Purchase on Sigma-Aldrich

概述

Replacement Information
Description
Catalogue NumberSCT052
DescriptionBioTracker Far-Red Peroxynitrite Live Cell Dye
OverviewReactive oxygen species (ROS) and nitrogen species (RNS) are implicated in various physiological and pathological processes. Among ROS and RNS, peroxynitrite (ONOO−) has attracted much special attention because of the key roles that it plays in signal transduction and antimicrobial activities. Peroxynitrite is endogenously produced by reaction of nitric oxide (NO) and superoxide radical anion (O2), however, ONOO− is more cytotoxic than NO or O2 alone, contributing to numerous pathologies such as cardiovascular disease and injury, diabetes, and cancer.

The BioTracker Far-Red Peroxynitrite live cell dye can be used for ONOO- detection. This probe is cell permeable and displays a high sensitivity and selectivity towards peroxynitrite over other ROS/RNS.
This probe can be used to detect exogenous and endogenous peroxynitrite in living systems and displays long wavelength absorption (600 nm) and emission (638 nm) bands.

Spectral Properties
Absorption: 600 nm
Emissions: 638 nm

References
Wu D et al. A Far-Red-Emitting Fluorescence Probe for Sensitive and Selective Detection of Peroxynitrite in Live Cells and Tissues. Anal Chem. 2017, 89, 10924-10931.
Alternate Names
  • Live cell imaging probe
References
Product Information
Detection methodFluorescence
PresentationLyophilized
Applications
ApplicationLive cell imaging probe for detection and imaging peroxynitrite, a highly cytotoxic reactive nitrogen species (RNS).
Key Applications
  • Cell Based Assays
Application NotesLive cell fluorescent imaging
Biological Information
Molecular Weight480.60 g/mol
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssurancePurity: ≥ 98% confirmed by HNMR, LC-MS and HPLC and elemental analysis
Molar Mass: 480.60 g/mol
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore BioTracker Far red Peroxynitrite Live Cell Dye at -20°C, desiccate and protect from light
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
Packaging Information
Material Size1 mg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
SCT052 04054839008399