208773 Sigma-AldrichCalpain Substrate IV, Cell-Permeable, Fluorogenic - Calbiochem
The non-permeant fluorogenic Calpain Substrate III is made cell-permeable by a c-terminal heptaarginine extension via a Glu linkage.
More>> The non-permeant fluorogenic Calpain Substrate III is made cell-permeable by a c-terminal heptaarginine extension via a Glu linkage. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: (DABCYL)-TPLK~SPPPSPRE(EDANS)-RRRRRRR-NH₂
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概述
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Products
| 产品目录编号 | 包装 | 数量 / 包装 | |
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| 208773-1MGCN | 塑胶安瓿;塑胶针药瓶 |
| Description | |
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| Overview | The non-permeant fluorogenic Calpain Substrate III (Cat. No. 208771) is made cell-permeable by a c-terminal heptaarginine extension via a Glu linkage. In addition to the expected improvement in permeability, the modified peptide also exhibits enhanced Calpain B sensitivity (kcat = 0.2 s-1, kcat/KM = 5000 M-1 s-1) when compared to the parental peptide (kcat = 0.17 s-1, kcat/KM = 680 M-1 s-1). Its suitability in detecting cellular Ca2+-dependent calpain activity is demonstrated both in intact Drosophila melanogaster S2 cells following ionomycin stimulation and in S2 lysates via direct Ca2+ addition. |
| Catalogue Number | 208773 |
| Brand Family | Calbiochem® |
| Synonyms | (DABCYL)-TPLK~SPPPSPRE(EDANS)-RRRRRRR-NH₂ |
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| References | Banoczi, Z., et al. 2008. Bioconjug. Chem. 19, 1375. |
| Product Information | |
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| Form | Lyophilized solid |
| Formulation | Supplied as a trifluoroacetate salt |
| Hill Formula | C₁₂₇H₂₀₆N₅₀O₂₇S |
| Chemical formula | C₁₂₇H₂₀₆N₅₀O₂₇S |
| HS Code | 3824 99 89 |
| Hygroscopic | Hygroscopic |
| Quality Level | MQ100 |
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| Purity | ≥95% by HPLC |
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| Peptide Sequence | (DABCYL)-Thr-Pro-Leu-Lys~Ser-Pro-Pro-Pro-Ser-Pro-Arg-Glu(EDANS)-Arg-Arg-Arg-Arg-Arg-Arg-Arg-NH₂ |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| 产品目录编号 | GTIN |
| 208773-1MGCN | 04055977202878 |
Documentation
Calpain Substrate IV, Cell-Permeable, Fluorogenic - Calbiochem MSDS
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Calpain Substrate IV, Cell-Permeable, Fluorogenic - Calbiochem 分析证书
| 标题 | 批号 |
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| 208773 |
参考
| 参考信息概述 |
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| Banoczi, Z., et al. 2008. Bioconjug. Chem. 19, 1375. |