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EZCCP-47K Canine C-peptide ELISA

This Canine C-Peptide ELISA is used to measure & quantify C-Peptide levels in Metabolism & Endocrine research.

Canine C-peptide ELISA MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: ELISA Detection Methods: Fluorescent, Colorimetric Research Category: Metabolism Research Sub-Category: Obesity, Metabolic Disorders
EZCCP-47K
96-well strip plate  
Purchase on Sigma-Aldrich

概述

Replacement Information

重要规格表

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
C-Peptide CaELISAFluorescent Colorimetric
Description
Catalogue NumberEZCCP-47K
DescriptionCanine C-peptide ELISA
Background InformationC-peptide is a byproduct of normal insulin production by the beta cells in the pancreas and correlates directly to endogenous concentrations of insulin.
References
Product Information
Detection methodFluorescent Colorimetric
Precision, %
  • Inter Assay: <15%
  • Intra Assay:<10%
Quality LevelMQ200
Applications
ApplicationThis Canine C-Peptide ELISA is used to measure & quantify C-Peptide levels in Metabolism & Endocrine research.
Key Applications
  • ELISA
Application Notes3 hour assay, room temperature 20 μL sample size
Biological Information
Species Reactivity
  • Canine
Analytes Available
  • C-Peptide
Entrez Gene Number
Entrez Gene SummaryAfter removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region.
Gene Symbol
  • INS
  • proinsulin
  • insulin
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
SIZE: 110 amino acids; 11981 Da
SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family.
Accuracy
  • 95%
Physicochemical Information
Sensitivity
  • 0.24 ng/mL
Linearity of Dilution96-118%
Standard Curve Range
  • 0.2-10 ng/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • For research use only. Not for use in diagnostic procedures.
Storage and Shipping Information
Packaging Information
Material Size96-well strip plate
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
EZCCP-47K 04055977315363