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05-23-5501 Sigma-AldrichParathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem

N-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca²⁺ and phosphate metabolism.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
52232-67-4	C₁₈₁H₂₉₁N₅₅O₅₁S₂

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Description
Overview	N-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca²⁺ and phosphate metabolism. Regulates Ca²⁺ and phosphate flux across cellular membranes in bone and kidney, resulting in increased serum Ca²⁺ levels. Increases the activity of osteoblasts and osteoclasts. Increases tubular reabsorption of Ca²⁺ and stimulates renal hydroxylation of 25-(OH)-Vitamin D₃ to 1,25-(OH)₂-Vitamin D₃. Increases the production of inhibitory IGF binding protein 4 in bone cells.
Catalogue Number	05-23-5501
Brand Family	Calbiochem®

References
References	Matsui, H., et al. 1995. Am. J. Physiol. 268, R21. Dua, K., et al. 1994. Exp. Physiol. 79, 401.

Product Information
CAS number	52232-67-4
ATP Competitive	N
Form	White to off-white lyophilized solid
Formulation	Supplied as an trifluoroacetate salt.
Hill Formula	C₁₈₁H₂₉₁N₅₅O₅₁S₂
Chemical formula	C₁₈₁H₂₉₁N₅₅O₅₁S₂
HS Code	3002 15 90
Reversible	N
Sold on the basis of peptide content	Y
Quality Level	MQ100

Applications

Biological Information
Primary Target	Homeostatic control of Ca2+ and phosphate metabolism
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N
Peptide Content	Y
Peptide Sequence	H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Moisture	Protect from moisture
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
05235501-1MGCN	04055977226850

Documentation

Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem 分析证书

标题	批号
05-23-5501	输入批号

参考

参考信息概述
Matsui, H., et al. 1995. Am. J. Physiol. 268, R21. Dua, K., et al. 1994. Exp. Physiol. 79, 401.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	4-October-2018 JSW
Description	N-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca²⁺ and phosphate metabolism. Regulates Ca²⁺ and phosphate flux across cellular membranes in bone and kidney, resulting in increased serum Ca²⁺ levels. Increases the activity of osteoblasts and osteoclasts. Increases tubular reabsorption of Ca²⁺ and stimulates renal hydroxylation of 25-(OH)-Vitamin D₃ to 1,25-(OH)₂-Vitamin D₃. Increases the production of inhibitory IGF binding protein 4 in bone cells.
Form	White to off-white lyophilized solid
Formulation	Supplied as an trifluoroacetate salt.
CAS number	52232-67-4
Chemical formula	C₁₈₁H₂₉₁N₅₅O₅₁S₂
Peptide Sequence	H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH
Purity	≥95% by HPLC
Solubility	5% acetic acid (1 mg/ml)
Storage	Protect from moisture -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
Merck USA index	14, 7034
References	Matsui, H., et al. 1995. Am. J. Physiol. 268, R21. Dua, K., et al. 1994. Exp. Physiol. 79, 401.

产品目录编号	描述
512585	Parathyroid Hormone 1-34, Rat

种类

Life Science Research > Inhibitors and Biochemicals > Biochemicals > Hormones > Other Hormones

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05-23-5501 Sigma-AldrichParathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem

N-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca²⁺ and phosphate metabolism.

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概述

重要规格表

Products

Documentation

Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem MSDS

Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem 分析证书

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N-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca2+ and phosphate metabolism.

Recommended Products

重要规格表

Products

Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem MSDS

Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem 分析证书

参考

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N-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca²⁺ and phosphate metabolism.